Orofacial clefts (OFC) are among the commonest birth defect in developed and developing countries alike. In underdeveloped countries, babies born with oral generally anaemic low weight may be unfit for surgery. The surgical reconstruction is also challenging aesthetic outcome cannot guaranteed by surgeon. Presurgical nasoalveolar moulding (PNAM) has been suggested to bridge gap between clefted ...

INTRODUCTION Cleft lip and palate are among the most common congenital anomalies worldwide. This study was conducted in order to explore the incidence and related factors of cleft lip and/or palate (CL/P) among live births in Mashhad, North-Eastern Iran. MATERIALS AND METHODS In this cross-sectional study, records of 28,519 infants born between March 1982 and March 2011 at three major hospita...

This article presents general aspects of risk factors and particularities of the management of individuals with oral clefts (OCs). A practical manual of prevention and management of this congenital defect was prepared based on a review of the literature and using data from Brazilian multicenter studies. Since OCs require efforts from all levels of healthcare, the data herein presented permits a...

OBJECTIVE To examine the association between maternal smoking and non-syndromic orofacial clefts in infants. METHODS A meta-analysis of the association between maternal smoking during pregnancy was carried out using data from 24 case-control and cohort studies. FINDINGS Consistent, moderate and statistically significant associations were found between maternal smoking and cleft lip, with or...