BACKGROUND All previous studies that investigated the association between abdominal fat distribution and insulin resistance evaluated subcutaneous and visceral fat area and/or volume, but these values were not related to the body type of each subject. In the present study we have examined the association between abdominal fat distribution and peripheral (muscle)/hepatic sensitivity to insulin u...

The relative impacts of regional and generalized adiposity on insulin sensitivity have not been fully defined. Therefore, we investigated the relationship of insulin sensitivity (measured using hyperinsulinemic, euglycemic clamp technique with [3-3H]glucose turnover) to total body adiposity (determined by hydrodensitometry) and regional adiposity. The latter was assessed by determining subcutan...

In Japanese Americans, intra-abdominal fat area measured by computed tomography is positively associated with the prevalence and incidence of hypertension. Evidence in other populations suggests that other fat areas may be protective. We sought to determine whether a change in specific fat depots predicts the development of hypertension. We prospectively followed up 286 subjects (mean age, 49.5...

BACKGROUND Both body fat distribution and adipocyte size are associated with metabolic abnormalities. OBJECTIVE We defined the extent to which subcutaneous adipocyte size is related to regional fat mass and to the sizes of adipocytes in other subcutaneous depots independent of adiposity, age, and sex. DESIGN Data collected from 188 women and 133 men who were 18-50 y old and who had a body m...

Lipid contents and compositions were measured in 35 pigs from seven genotype-sex groups with large variations in body composition. The animals were slaughtered at 115kg live weight, and the left side was separated into four primal cuts: belly, ham, loin, and shoulder. Samples of adipose tissues were taken from flare fat and from subcutaneous and intermuscular adipose tissues in each of the four...

Introduction: Electromagnetic radiofrequency (RF) sources are widely used to heat up cutaneous and subcutaneous tissues for different applications, such as, generation of new dermal collagen and denaturation of adipocytes or fat cells. The subcutaneous morphology of tissue consists of a fine, collagenous and fibrous septa network enveloping clusters of adipocyte cells [1]; however, it is common...

Animals accumulate fat in tissues as subcutaneous, intermuscular, intramuscular, and abdominal fat. Genetic interrelationships of respective fat depositions, however, have not been examined in depth. This study estimated genetic parameters for subcutaneous, intermuscular, and abdominal fat areas of 545 Duroc purebred pigs slaughtered at 105 kg of BW. Measurements were obtained using an image an...

OBJECTIVE The purpose of this study was to determine whether cyclooxygenase inhibition improves vascular dysfunction of adipose microvessels from obese humans. DESIGN AND METHODS In 20 obese subjects (age 37 ± 12 years, BMI 47 ± 8 kg/m²), subcutaneous and visceral fat were collected during bariatric surgery and characterized for adipose depot-specific gene expression, endothelial cell phenoty...

PURPOSE Chondromalacia patellae is a common cause of anterior knee pain in young patients and can be detected noninvasively with magnetic resonance imaging (MRI). The purpose of our study was to evaluate the correlation between subcutaneous fat thickness around the knee joint on axial MRIs as a surrogate marker of obesity, with the presence or absence of chondromalacia patellae. METHODS A ret...

In addressing the topic of “The Relationship of Animal Leanness to Meat Tenderness,” I think it is extremely important to establish how much variability in tenderness exists and the extent to which the lack of tenderness is a problem. In addition, it is important to establish a definition or description of “animal leanness.” Carcasses may be lean because animals were fed beta-agonists, injected...