Soluble proteins of rhabdomyosarcoma and normal muscle were chromatographed and separated into a number of peaks by gradient elution from DEAE cellulose. The chromatographic patterns were different in the two tissues studied. Various enzymatic activities were determined in the fractions and localized in the chromatograms of both muscle and rhabdomyosarcoma. Some of the enzymes tested appeared i...

Rhabdomyosarcoma is the malignant neoplasm of striated muscle and a relatively uncommon tumor of the oral cavity. Embryonal variety is the most common subtype, observed in children below 10 years of age but occasionally seen in adolescents and young adults. The present report describes a case of embryonal rhabdomyosarcoma in the left posterior buccal mucosa, with extension in the adjacent alveo...

We report a case of rhabdomyosarcoma of the middle ear and mastoid in a 3-year-old boy. The patient was treated according to Intergroup Rhabdomyosarcoma Study IV protocol (chemo- and radiotherapy), and he experienced a complete remission. However 7 months after the completion of treatment, he experienced a recurrence at the primary site that spread to the brain. Despite treatment, the patient d...

Paratesticular rhabdomyosarcoma is a rare malignancy arising from the mesenchymal tissues of the spermatic cord, epididymis, testis, and testicular tunica, and accounts for approximately 7% of all rhabdomyosarcomas. It often occurs in children but is known to have a better prognosis than disease at other urogenital sites. Patients typically present with painless unilateral scrotal swelling like...

Embryonal rhabdomyosarcoma is an exceedingly rare tumor in adult. We report an embryonal rhabdomyosarcoma of the ethmoid in a 59-year-old Iban lady who presented with proptosis and complete ptosis of her left eye for two months. Imaging investigations showed left ethmoidal and left orbital soft tissue mass with extradura and dura involvement. The patient was planned for chemotherapy. Unfortunat...

A 50-year-old woman with metastatic rhabdomyosarcoma of the ovary had increased activities of creatine kinase (CK; EC 2.7.3.2), CK-MB isoenzyme, lactate dehydrogenase (LD; EC 1.1.1.27), and LD-2 isoenzyme in her serum. The isoenzyme activities did not show a pattern of increasing, then decreasing. Clinical findings, including electrocardiograms, did not support the diagnosis of myocardial infar...

Extraskeletal Ewing sarcoma is covered by other ESMO Guidelines: in general, the same principles for these tumours in children apply to adults. This is also the case for embryonal and alveolar rhabdomyosarcoma, which are exceedingly rare in adults. On the other hand, pleomorphic rhabdomyosarcoma is viewed as a high-grade adult-type soft tissue sarcoma. Gastrointestinal stromal tumours are cover...

Urinary bladder rhabdomyosarcoma from a 9-month-old female Labrador retriever dog is described. Grossly reddish black multiple friable multinodular masses filled the lumen of the urinary bladder. Histologically, the masses consisted of round, fusiform and polygonal cells with various consistencies. There were also some strap-like cells with chained nuclei and cross-striations. It was diagnosed ...

Rhabdomyosarcoma (RMS) is one of the more common solid tumors in children, with approximately 250 new cases diagnosed each year.1 The roles of pediatric surgeons in the treatment of RMS have changed signiŽ cantly through the years, as other adjuvant therapies have become more efŽ cacious. The purpose of this manuscript is to describe the current surgical therapy recommendations of the Soft Tiss...

Extraskeletal Ewing sarcoma is covered by other ESMO Guidelines: in general, the same principles for these tumours in children apply to adults. This is also the case for embryonal and alveolar rhabdomyosarcoma, which are exceedingly rare in adults. On the other hand, pleomorphic rhabdomyosarcoma is viewed as a high-grade adult-type soft tissue sarcoma. Gastrointestinal stromal tumours are cover...