نتایج جستجو برای: جهش زایی نقطه ای sdm

تعداد نتایج: 255799  

2004
DAMJAN VAVPOTIC MARJAN KRISPER

Theoretical research in the field of software development methodologies (SDM) shows that the use of SDM should improve the efficiency of the development team and the quality of the developed product, nevertheless in practice not many software development organizations use SDM. In our paper we present a research that provides a theoretical background for measuring the SDM suitability on two dime...

2015
Naidong WANG Anwen YUAN Jun MA Zhibang DENG Liqun XUE

The use of serologically detectable male (SDM; also called H-Y) antigens to identify male embryos may be limited by the source of anti-SDM antibody. In the present study, novel anti-SDM B9-Fab recombinant clones (obtained by chain shuffling of an A8 original clone) were used to detect SDM antigens on murine embryos. Murine morulae and blastocysts (n=138) were flushed from the oviducts of Kunmin...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شیراز - دانشکده علوم پایه 1392

آلفاکریستالین ها با دو زیرواحد a و b دارای بالاترین غلظت در بین پروتئین های محلول لنز است. این پروتئین متعلق به خانواده ی پروتئین های شوک حرارتی می باشد و با ساختاردومی سرشار از صفحات بتا، هتروالیگومرهایی با اندازه های 250 تا 800 کیلودالتون تشکیل می دهد. آلفاکریستالین علاوه بر نقش ساختاری، با فعالیت چاپرونی از رسوب دیگر پروتئین ها در لنز جلوگیری می کند و مانع از بروز بیماری آب-مروارید می شود. ج...

2010
France Légaré Hilary Bekker Sophie Desroches Mary Politi Dawn Stacey Francine Borduas Francine M Cheater Jacques Cornuz Marie-France Coutu Norbert Donner-Banzhoff Nora Ferdjaoui-Moumjid Frances Griffiths Martin Härter Cath Jackson André Jacques Tanja Krones Michel Labrecque Rosario Rodriguez Michel Rousseau Mark Sullivan

BACKGROUND Shared decision making (SDM) is a process by which a healthcare choice is made jointly by the healthcare professional and the patient. SDM is the essential element of patient-centered care, a core concept of primary care. However, SDM is seldom translated into primary practice. Continuing professional development (CPD) is the principal means by which healthcare professionals continue...

2014
Monica E. Peek Melinda Drum Lisa A. Cooper

BACKGROUND Shared decision making (SDM) is associated with positive health outcomes and may be particularly relevant for patients with chronic disease. OBJECTIVES To investigate whether (1) patients with chronic diseases, particularly those requiring self-management, are more likely to engage in SDM behaviors than patients without chronic diseases and (2) patients with chronic diseases are mo...

2015
Rongchong Huang Michael R Gionfriddo Lizhi Zhang Aaron L Leppin Henry H Ting Victor M Montori

BACKGROUND Severe insufficiencies in the supply and inequities in the distribution of health care professionals, facilities, and services create conditions for limited quality of care and lack of trust - even violent conflict - between clinicians and patients in the People's Republic of China. Alongside structural reform, shared decision-making (SDM) may help meet the needs and advance the goal...

2014
Paul James Barr Rachel Thompson Thom Walsh Stuart W Grande Elissa M Ozanne Glyn Elwyn

BACKGROUND Patient-centered health care is a central component of current health policy agendas. Shared decision making (SDM) is considered to be the pinnacle of patient engagement and methods to promote this are becoming commonplace. However, the measurement of SDM continues to prove challenging. Reviews have highlighted the need for a patient-reported measure of SDM that is practical, valid, ...

2006
Uma Ramamurthy Stan Franklin

This paper presents research on the development of effective forgetting mechanisms for the Sparse Distributed Memory (SDM) system, to computationally model Transient Episodic Memory (TEM), a short-term sensory perceptual episodic memory in software agents. Possible theories and mechanisms for forgetting are retrieval failures, decay and interference. The SDM architecture has inherent features t...

2005
Sidney K. D’Mello Uma Ramamurthy

This paper presents detailed simulation results on a modified Sparse Distributed Memory (SDM) system. We have modified Kanerva’s original SDM system into an architecture with a ternary memory space. This enables the memory to be used as a Transient Episodic Memory (TEM) in cognitive software agents. TEM is a memory with high specificity and low retention, used for events having features of a pa...

Journal: :Circulation. Cardiovascular quality and outcomes 2014
Erik P Hess Megan Coylewright Dominick L Frosch Nilay D Shah

D espite recent health policy recommendations supporting shared decision making (SDM), a rapidly growing evidence base supporting the desirable effects of tools to facilitate SDM, availability of SDM tools specifically designed for cardiovascular care (Table 1), 1 and recent advocacy for SDM in cardiovascular guidelines, 2,3 SDM has not been widely incorporated into routine clinical practice. A...

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