Steady state fluorescence measurements have been used for the investigation of interaction between the bovine serum albumin (BSA) and fluorescence probes: 3-hydroxy-2,4- bis[(3-methyl-1,3-benzoxazol-2(3H)-ylidene)methyl]cyclobut-2-en-1-one (SQ6), 3-hydroxy- 2,4-bis[(3-methyl-1,3-benzothiazol-2(3H)-ylidene)methyl]cyclobut-2-en-1-one (SQ7) and 3-hydroxy-2,4-bis[(1,3,3-trimethyl-1,3-dihydro-2H-ind...

We have worked out a procedure for covalent binding of native biomacromolecules on flat gold surfaces for scanning probe microscopy in aqueous buffer solutions and for other nanotechnological applications, such as the direct measurement of interaction forces between immobilized macromolecules, of their elastomechanical properties, etc. It is based on the covalent immobilization of amino group-c...

Femtosecond-laser-written integrated waveguides enable multi-wavelength fluorescence sensing of flowing biomolecules in an optofluidic chip. Fluorescence from differently labeled biomolecules with distinct absorption wavelengths, encoded by uniquely modulating each excitation beam, is detected by a color-blind photodetector, and the origin of each signal is unraveled by Fourier analysis. Keywor...

Why is it that different organisms do so many different things with sulfur?  Sulfur exists in many different oxidation states  Reduced sulfur is required for many biomolecules  Sulfur forms can serve as an electron sources or as electron acceptors  Oxidation states of sulfur  Sulfur assimilation in bacteria and yeasts  Sulfur-containing biomolecules  Sulfide Oxidation  Sulfate Reduction...

Endothelial Progenitor Cell (EPC) based therapies continue to be of interest to treat ischemic events based on their proven role to promote blood vessel formation and thus tissue revascularisation. Current strategies for the production of clinical-grade EPCs requires the in vitro isolation of EPCs from peripheral blood followed by cell expansion to provide sufficient quantities EPCs for cell th...

In this work gate-on-drain L-shaped channel Tunnel FET is proposed to detect various biomolecules through label-free bio-sensing detection technique. Biomolecules can be detected in the structure modulation of ambipolar current between and drain. Modulation performed by extending gate over drain order create a overlap (cavity) etching specific portion gate. Trapped within cavity gets immobilize...