polyarteritis nodosa is a multisystem necrotizing vasculitis of small and medium size muscular arteries in which involvement of the renal and viserat arteries is characteristic. the etiology is unknown but hepatitis b antigenemia is found in 30% of patients. drug exposures and hypersensitivity reactions are other possible causes. excellent therapeutic results have been reported in classic polya...

subcutaneous panniculitis-like t-cell lymphoma (sptcl) is an infrequent cytotoxic t-cell lymphoma of the skin with a unique immunophenotypic profile. here we describe this lymphoma in a 30-year-old iranian woman. she presented with periorbital edema, mandibular swelling with edematous areas on her face and two small lymph nodes (6-7mm) in the cervical area. histopathological findings revealed l...

Results Of 286HIV-infected patients, 12 were children (4.1%), 8 (66.7%) of whom were male. Ages at diagnosis ranged from 6 months to 12 years (median 5). Of the 10 (83.3%) children who acquired the infection by vertical transmission, median age at diagnosis was 3 years. Only one woman was offered PMTCT interventions with HAART started lately at 38 weeks of pregnancy, oral AZT and replacement fe...

This case study discusses in detail for the first time the diagnosis and management of a case of leishmaniosis in a dog imported to Australia. The dog presented with epistaxis and a non-regenerative anaemia five years after being imported from Europe. Protozoa were identified within macrophages in bone marrow and splenic cytology. A Leishmania indirect fluorescent antibody test was performed an...

Biallelic mutations in several genes associated with cytotoxic lymphocytes function has been related to Familial HLH (FHLH). The clinical presentation of primary and acquired may be indistinguishable, both forms are commonly triggered by infections. FHLH is well described children but the last decade late-onset cases have reported. We report immunological characteristics two adult patients carr...

Miltefosine-Allopurinol (MIL-AL) combination is reported to be one of the most effective treatments for canine leishmaniosis, thanks its oral administration and MIL-documented low impact on renal function. However, MIL-AL considered a second-choice treatment when compared meglumine-antimoniate—allopurinol combination, mainly due risk earlier relapses. The aim this study was evaluate efficacy pr...