The American Journal of Physiology: Regulatory, Integrative and Comparative Physiology (ISSN0363-6119) is published monthly (two volumes a year) by the American Physiological Society, 9650 Rockville Pike, Bethesda, MD 20814. Subscription Price: $60.00 per year U.S.; $75.00 elsewhere. Subscriptions from outside the United States are payable in U.S. currency or full equivalent. Subscriptions are ...

1 Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America, 2 ClinicalTrials.gov, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America, 3 Department of Clinical Bioethics, Warren G. Magnusen Clinical Center, National Institutes of Health, Bethesda, Mar...

From the * University of Montreal, Centre de Recherche Louis-Charles Simard, Hôpital Notre-Dame, Montreal, Quebec H2L 4M1, Canada; the ‡ Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, Maryland 20889; the § Division of Retrovirology, Walter Reed Army Institute for Research, Rockville, Maryland 20850; the i Experimental Immunology Branch, National Institutes of He...

Erratum to “Neuroepigenomics: resources, obstacles, and opportunities” [Neuroepigenetics 1 (2015) 2-13] John S. Satterlee⁎, Andrea Beckel-Mitchener, A. Roger Little , Dena Procaccini , Joni L. Rutter , Amy C. Lossie c a Division of Basic Neurobiology and Behavioral Research, National Institute on Drug Abuse (NIDA), 6001 Executive Blvd, Bethesda, MD 20892-9641, USA b Division of Neuroscience and...

The determination of the factors influencing the effectiveness of algorithm visualization poses an interesting research question. In this paper, we present the results of a longitude empirical study regarding this question. The study was based on an evaluation of the Visual LinProg educational tool inside classrooms. Visual LinProg is a web-based educational tool, which solves linear programmin...

Linear Programming is a significant and well-studied optimization methodology. Simplex type algorithms have been widely used in Decision Support Systems. The computation of the basis inverse is a crucial step in simplex type algorithms. In this paper, we review and compare three basis update methods. We incorporate these methods on the exterior and the revised simplex algorithm in order to high...

From the Section on Neuroendocrinology, Program on Developmental Endocrinology and Genetics, NICHD, National Institutes of Health, Bethesda, Maryland 20892, School of Biosciences, Cardiff University, Cardiff CF10 3AX, United Kingdom, Genomics Institute, Novartis Research Foundation, San Diego, California 92121, Department of Neuroscience and Pharmacology, Faculty of Health Sciences, University ...

Gary Levy1, Micah J. Hill1, Christina I. Ramirez1, Luiz Correa2, Mary E. Ryan3, Alan H. DeCherney1, Eric D. Levens4, and Brian W. Whitcomb5,* Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA Tripler Army Medical Center, Honolulu, HI, USA National Institutes of Health...

Hemoglobin Bethesda is a /3 chain variant of human hemoglobin in which histidine is substituted for tyrosine at position 145. From chemical and crystallographic studies, it has been postulated that the tyrosine normally found at this position is critical for the maintaince of a normal deoxy structure. Kinetic studies of the carbon monoxide and Rbutyl isocyanide binding reactions show that deoxy...