multiple sclerosis (ms) is an inflammatory disorder, in which neurons become demyelinated. to date, its etiology has remained unknown. nevertheless, certain features are inspected to provoke ms. for instance, improper function of immune cells is widely believed to be the basis of such disorder. in this concept, ms is stated as an autoimmune disease, which was asserted by major of studies, as cd...

introduction: human leukocyte antigen (hla) genes are the most polymorphic loci in the human genome. they predict the outcome of transplantation by detecting self from non-self antigens. the best use of hla typing is to find a hla-match donor for bmt candidate patients. evidence suggests that matching unrelated donors and recipients for hla-a, -b and -drb1 loci is a prediction for an improved o...

umbilical cord blood (ucb) as a source of hematopoietic stem/progenitor cells (hspcs) used for umbilical cord blood transplantation (ucbt). the main obstacle in application of this source as an appropriate source of hspcs is low volume of this product. so ex vivo expansion of these cells in a microenvironment which mimic body condition is important. in current study we designed biocompatible mi...

objective(s) bone is a dynamic tissue that is continuously renewed throughout life by the process of bone remodeling. antioxidant system might be involved in the pathogenesis of bone loss, so the aim of this study was to evaluate the total antioxidant capacity (tac), vitamin c and vitamin e levels of plasma besides measuring enzymatic antioxidants, superoxide dismutase (sod), catalase (cat) and...

blood sulfhemoglobin (s-hb), total haemoglobin and phosphorous (p) level and blood cell count in 33 matches industry workers of azar abhar, who were exposed directly or indirectly to chemical agents used in the factory (subjects), were measured. the results were compared with the result of the same measurement on 14 farm workers of the region (control) and were analysed. in this study the effec...

errors in blood pressure (bp) measurement are common in the clinical practice. inaccurate measurements of bp may lead to misdiagnosis and inappropriate treatment of hypertension. the preferred method of bp measurement in the clinical setting is a scultation, using the first and the fi fth korotkoff sounds. however, the use of mercury sphygmomanometer is declining. automated oscillometric device...

adenosine has many of the characteristics of a regulator of cerebral blood flow and adenosine receptors change in morphine dependency. in this study the changes in adenosine receptors' responsiveness of pial vessels in the hind limb area of the sensory cortex were evaluated in morphine dependent rats (mdr) using the laser doppler flowmetry technique. adult male sprague dawley rats (250-350...

introduction hepatitis b infection remains a major health problem worldwide and is an important cause of morbidity and mortality. since it is transmitted parenterally, investigation of new cases of hepatitis b infections for potential routes of transmission plays a crucial role in controlling hepatitis b infection in the community. case presentation in this study, we reported a new case of hepa...

this study was conducted to evaluate the effects of different proportions of lemon bee brush essential oil on growth performance, carcass composition, and hematology and biochemical parameters of common carp (cyprinus carpio). common carp with an average weight of 8 ± 0.2 g were fed for one month with a diet supplemented with lemon beebrush essential oil (0.15 and 0.3 ml) and with normal diet a...

background: considering their specific adaption to marine milieus, marine actinomycetes constitute an excellent source for producing unique bioactive substances. they are also important sources of antibiotics and extracellular enzymes, geosmin, and enzymes with potent antibacterial and anticarcinogenic properties and low toxicity. the objective of this study is to isolate actinomycetes producin...