hdl can prevent ldl-c oxidation. the low hdl-c state also may benefit clinically from supplemented antioxidant. this study was designed to evaluate the combination therapy of statin and vitamin e in hypercholesterolemic patients. the patients were randomized in a clinical trial aimed to avaluate the effect of vitamin e and/or statin.the life style of patients didn't alter during intervention. t...

conclusions in conclusion, we have shown that vitamin c administration provides protection against csa-induced injury in rat liver function and may have hepatoprotective role in the patients experiencing csa treatment. background cyclosporine a (csa) is an important immunosuppressive agent; however, its clinical use is limited by several side effects such as hepatotoxicity. vitamin c (ascorbic ...

background chronic inflammation is the most important cause of cardiovascular disease in patients undergoing hemodialysis, and vitamin c as a major antioxidant which could be effective to suppress inflammation. objectives this study was performed to evaluate the effect of vitamin c supplementation on c-reactive protein levels in patients undergoing hemodialysis. patients and methods this random...

the total vitamin c content in human plasma is widely accepted as an indicator of the tissue status of vitamin c. a liquid chromatography method with ultraviolet detector (264 nm) for measuring ascorbic acid in human plasma was developed. a c18 reversed-phase column and cetrimide as an ion-pairing agent was employed. ascorbic acid (aa) was measured after reducing l-dehydroascorbic acid to l-asc...

background: hypercholesterolemia is one of the risk factors of cardiovascular diseases. it affects general health and increases cardiovascular mortality rate. diet with high cholesterol increases ldl that, inturn, decrease ldl receptors activity in liver. oxidation of vessel wall lipoproteins increases development of atherosclerosis. several evidences suggest that antioxidants consumption decre...

the effect of subcutaneous injections of vitamin c on the seminal characteristics of markhoz bucks (2–4-year-old) was studied. the bucks, trained to serve an artificial vagina, were randomly allotted into three equal groups (n = 4) and received daily either zero (1 ml normal saline; control group), or 20 (vitc20 group) or 40 (vitc40 group) mg per kg body weight vitamin c from july 06, 2006 to o...

conclusions considering that no significant difference was found in the proven vitamin a side effects, due to the increase in crp, frequent clinical and biochemical controls are required along with vitamin a supplementation. patients and methods this study was a double blind randomized clinical trial. in the main study, vitamin a (as retinyl palmitate) was given to 35 multiple sclerosis (ms) pa...

in order to study of vitamin c effect on body composition and antioxidant enzyme activities, including superoxide dismutase and catalase in five diets containing different levels of vitamin c (0, 50, 250, 750and 1500mg vitamin/kg diet) had been fed by caspian brown trout fry (salmo trutta caspius) for 6 weeks in triplicate. after 6 weeks, the findings of growth parameters and survival showed si...