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BACKGROUND Some syphilis patients remain in a serologically active state after the recommended therapy. We currently know too little about the characteristics of this serological response. METHODS We conducted a cohort study using the clinical database from Zhongshan Hospital, Medical College of Xiamen. In total, 1,327 HIV-negative patients with primary, secondary, latent, and tertiary syphil...

Diagnostic tests for active tuberculosis (TB) based on the detection of antibodies (serological tests) have been commercially available for decades, although no international guidelines have recommended their use. An estimated 1.5 million serological TB tests, mainly enzyme-linked immunosorbent assays, are performed in India alone every year, mostly in the private sector. The cost of serologica...

OBJECTIVE The aims of this study were to describe the clinical presentation of primary SS (pSS) in a large cohort of patients by assessing the prevalence of the patient subgroups at high risk for severe extraglandular manifestations and to explore the influence of the patients' serological profile on disease severity and on immunosuppressive drug utilization. METHODS Cumulative demographic, c...

Visceral leishmaniasis (VL) is a zoonotic disease caused by leishmania species. Dogs are considered to be the main reservoir of VL. A number of methods and antigen-based assays are used for the diagnosis of leishmaniasis. However, currently available methods are mainly based on direct examination of tissues for the presence of parasites, which is highly invasive. A variety of serological tests ...

Avian influenza is a zoonotic disease that can adversely affect humans and animals. Nigeria first reported an outbreak of avian which was caused by subtype H5N1 in 2006, thereafter virological serological surveys revealed the importance local birds live bird markets community at large epidemiology country. In present study, 276 serum samples were collected for testing over five months from appa...

Strategies for the prevention of cancer include those aimed at reducing the incidence of cancer (primary prevention) and cancer mortality through early detection of tumors (secondary prevention). The efficacy of prevention interventions is evaluated by clinical trials. The conduct of clinical trials is aided by the use of serological indicators of the carcinogenic process measured using plasma ...

a living body produces in the body antisubstances which react with the substance is an antigen. The anti-substance is an antibody which is found in the blood, plasma or serum and is contained in the serum globulin. Serological reactions are antigen-antibody reactions. They are also called immunological reactions or biological reactions. The serological technique sets up these reactions. It is a...