Rhabdomyosarcoma encompasses a group of malignant myogenic neoplasms expressing a multitude of clinical and pathological diversities. It is the commonest soft tissue sarcoma of childhood but neonates are rarely affected. Embryonal subtype is the most frequent. Head-neck and genitourinary tracts are predominant sites, while trunk is considered among the unusual sites of rhabdomyosarcoma. Herein ...

Rhabdomyosarcoma is a pediatric tumor type, which is classified based on histological criteria into two major subgroups, namely embryonal rhabdomyosarcoma and alveolar rhabdomyosarcoma. The majority, but not all, alveolar rhabdomyosarcoma carry the specific PAX3(7)/FKHR-translocation, whereas there is no consistent genetic abnormality recognized in embryonal rhabdomyosarcoma. To gain additional...

Spindle cell rhabdomyosarcoma is a rare variant of embryonal rhabdomyosarcoma that affects young males and most commonly involves the paratesticular region. We report a case of paratesticular spindle cell rhabdomyosarcoma in a 14-year-old boy, who presented with a painless scrotal mass. Left inguinal orchidectomy was performed. Histopathological and immunohistochemical examination of the mass r...

INTRODUCTION Rhabdomyosarcoma is the most common primary orbital malignant tumor in children. Orbital lesions represent about 10 % of all the cases of rhabdomyosarcoma. Rhabdomyosarcoma is a rare cause of proptosis in adults. OBJECTIVE To report a case of primary orbital rhabdomyosarcoma in a 45-year-old female. DESIGN Interventional case report. The main outcome measures are a rare cause o...

Rhabdomyosarcoma is the most common soft tissue malignancy of childhood, but may occur extremely rarely in the neonatal period. There are only a few reports of rhabdomyosarcoma in neonates. Although, it may arise anywhere in the body, the head and neck, and genitourinary regions are the most frequent sites. Truncal and chest wall rhabdomyosarcoma is relatively rare occurrence. We report a neona...

Connective tissue growth factor (CTGF/CCN2), a cysteine-rich protein of the CCN (Cyr61, CTGF, Nov) family of genes, emerged from a microarray screen of genes expressed by human rhabdomyosarcoma cells. Rhabdomyosarcoma is a soft tissue sarcoma of childhood deriving from skeletal muscle cells. In this study, we investigated the role of CTGF in rhabdomyosarcoma. Human rhabdomyosarcoma cells of the...

background: rhabdomyosarcoma (rms) is one of the common malignant tumors in infants and children, but it is extremely rare in the kidney. in this paper, we present a case of rms the kidney of a child. case presentation: a 6-month old girl presented with agitation, low fever and abdominal distention which started 5 days ago. on physical examination, the infant had a large and firm soft tissue ma...

The outcome of patients with advanced stage rhabdomyosarcoma is extremely poor, with a disease-free survival of less than 20% at 3 years. Autologous bone marrow transplantation for patients with Clinical Group IV rhabdomyosarcoma may be an effective therapy. The bone marrow involvement diagnosed by light microscopy is 29% for patients with advanced disease. The present study was performed to te...

Introduction: Rhabdomyosarcoma is a high-grade malignant neoplasm with skeletal muscle differentiation; common soft tissue sarcoma in children but considered one of the rarest adults. Case description: We report case 35-year-old male chronic productive cough and haemoptysis for five days. A CT scan nasopharynx revealed blocked left maxillary ethmoid sinus bone destruction. These findings raised...

we report a 73-year-old woman with primary left atrial rhabdomyosarcoma and its 1h mr spectroscopy (mrs) findings. the tumor showed a 2.8 cm sized lesion in the posteroinferior atrial wall on mri. 1h mr spectra were acquired using a point-resolved spectroscopy (press) sequence with electrocardiographic (ecg) gating and respiratory motion. the use of 1h-mrs allowed the quantification of triglyce...