BACKGROUND Previous studies have suggested that pulmonary embolism (PE) and pulmonary artery occlusion result in a shift in alveolar ventilation away from unperfused regions. This study aimed to directly assess changes in regional specific ventilation (sV(A)) due to autologous blood clot PE using positron emission tomography. METHODS Pulmonary embolism was created in six anesthetized, paralyz...

BACKGROUND Echocardiography combining Doppler and two-dimensional data is recommended for quantitative assessments of valvular regurgitation. We applied a new method to calculate the mitral annulus (MA) area in combination with multiple sample sites. Individuals without regurgitation in whom the valvular and left ventricular stroke volumes (SV) should be identical were investigated in order to ...

THEOREM. Let Ai, A2, • , Av be p sets of positive measure lying in euclidean n space. Then there exist p n-dimensional spheres Si, 52, • • • , Sp such that for every set of p points sv, (*> = 1,2, • • • , p), belonging respectively to these spheres, there exists a set of p points av, (v = 1, 2, • • • , p), lying respectively in A\, A2, • • • , Ap, such that the sets [av] and {sv} are congruent....

We used a 3C/3D seismic reflection data set from King County, Texas, to investigate the utility of multicomponent seismic data for improving reservoir characterization. We evaluated a new seismic processing/ interpretation option, based on direct-S modes generated by a vertical-force source. This new seismic mode, SV-P, may allow legacy 3D P-wave data to be reprocessed to create converted-wave ...

We expressed P-glycoproteins (P-gps) encoded by the three mouse mdr genes in the membranes of secretory vesicles (SV) accumulating in the yeast mutant strain sec 6-4. Expression of the Mdr1 and Mdr3 isoforms in SV membranes caused a significant increased accumulation of the drug vinblastine (VBL) over background levels measured in control SV. The Mdr1/Mdr3-mediated increased drug accumulation c...

INTRODUCTION Relationships between cardiac pressure and volume have been suggested as markers of cardiac contractility; parameters include stroke work and the maximal rate of pressure rise during isovolumic contraction (dP/dtmax). Patients with cancer often display dyspnea and fatigue. These are also frequent symptoms in patients with chronic heart failure (HF). The reasons for similar symptoms...

Separating P-P and P-SV waves can sometimes be a difficult task for multicomponent data. Simple FK filtering methods do not perform suitably if the moveout trajectory is similar for different events. Here the least-squares migration filtering (LSMF) method is modified to separate P-P and P-SV waves recorded in multicomponent CDP data set. We exploit the property that different wave types have d...

Previous studies using echocardiography in healthy subjects have reported conflicting data regarding the percentage of the stroke volume (SV) of the left ventricle (LV) resulting from longitudinal and radial function, respectively. Therefore, the aim was to quantify the percentage of SV explained by longitudinal atrioventricular plane displacement (AVPD) in controls, athletes, and patients with...

BACKGROUND Radial artery (RA) aortocoronary bypass grafts anastomosed to a branch of the circumflex coronary artery have significantly better patency rates than saphenous vein (SV) grafts at 5 years, but the physiological characteristics and mechanisms involved are not clearly defined. We compared RA and SV graft vasomotor and flow responses to endothelium-dependent and -independent stimuli 5 y...