type 1 diabetes mellitus is frequently associated with autoimmune thyroid disease (atd).genetic susceptibility for autoantibody formation in association with atd and type 1 diabetes mellitus has been described with varying frequencies, but there is still debate about its prevailing situation in iran.  we have therefore investigated the prevalence of anti-thyroid peroxidase (anti-tpo) and anti t...

spirulina is free-floating filamentous microalgae growing in alkaline water bodies. as early as over 400 years ago, spirulina was eaten as food by the mayas, toltec’s and kanembu in mexico during the aztec civilization. spirulina is a well-known source of valuable food supplements, such as proteins, vitamins, amino acids, minerals, fatty acids, etc. it is widely used in human and animal nutriti...

background and objectives: adhesion and colonization are prerequisites for the establishment of bacterial pathogenesis. the biofilm development of pseudomonas aeruginosa was assessed on adhesive surfaces like dialysis membrane, stainless steel, glass and polystyrene. materials and methods: microtiter plate biofilm assay was performed to assess the effect of nutrient medium and growth parameters...

abstract       background and objective: glycyrrhizaglabra l. is one of the most widely used medicinal herbs in golestan province that is known for its anti-inflammatory, carminative, antiviral, anti-infection and anti-ulcer properties in iranian traditional medicine. this study aimed to assess the anti-bacterial and anti-oxidative activity of g. glabrafrom the golestan province.         method...

background: thiamine (vitb1) is a vitamin with various important physiological functions and postulated therapeutic effects.  its use as an analgesic in neuropathic pain has been undergoing in clinical settings. however, there has been little experimental investigation on this effect. in this study, anti-nociceptive and anti-inflammatory effects of thiamine were investigated in mice. methods: t...

there is the need for new drugs with better action and lesser side effects. a lot of research is being undertaken to find out new plant drugs, their extraction and pharmacological evaluation. one of such plant is curcuma aromatica whichbelongs to the genus curcuma and reported to have high ethno-botanical values in traditional medicine. the present study evaluates comparative pharmacological ac...

burns are known as one of the most common forms of injury with devastating consequences. despite the discovery of several antiseptics, burn wound healing has still remained a challenge to modern medicine. herbal products seem to possess moderate efficacy with no or less toxicity and are less expensive compared to synthetic drugs. burn is a well-known disorder in iranian traditional medicine (it...

in the present study, anti-anaphylactic, anti-inflammatory and membrane stabilizing properties of a lupine alkaloid plumerianine (compound 1), isolated from the root bark of plumeria acutifolia poir were investigated in animal models. the anti-anaphylactic activity of compound 1 (10, 25 and 50 mg/kg) was studied by using models such as passive cutaneous anaphylaxis, passive paw anaphylaxis and ...

background: evidences show that aloe vera (a. vera), camellia sinensis, hibiscus sabdariffa and sophora alopecuroides may prevent gastric ulcer induced by non-steroidal anti-inflammatory drugs (nsaids). objective: to examine the protective potential of these plants against indomethacin-induced gastric ulcer in the rat. methods: saline, a. vera leaf gel powder and 70% alcoholic extracts of the o...