osteoarthritis is the most common joint disease.the main pathologic manifestation of disease is local destruction of cartilage in diarthrodial joint. new bone formation in marginal surface of the joint is a sign progressive disease. many systemic and local factors are introduced in initiate and progression of osteoarthritis include: age, sex, weight, race, genetic background, bone densitometry,...

A dog was presented with history of progressive generalized subcutaneous emphysema and exercise intolerance secondary to dog fight. Radiographic evaluation confirmed extensive subcutaneous emphysema, pneumomediastinum and pneumoretroperitoneum. Surgical exploration revealed cricoid cartilage longitudinal fracture and cricotracheal detachment. The fractured cartilage was sutured and the cricoid ...

  Cartilage hair hypoplasia (CHH), is a rare cause of metaphyseal chondrodysplasia and short stature. Other features included hair abnormality, immunodeficiency, anemia, gastrointestinal disorders (Hirschsprung disease, celiac, …) and increased risk of cancer. The disease is an autosomal recessive disorder and previously has not been reported in Iran. We report a 9-year-old boy diagnosed as car...

extracelllar matrix (ecm) materials from mammalian tissues have been broadly used for tissue engineering for animal models. while decellularization of tissues such as bladder, heart valve, knee meniscus and tendon has been performed, there are a few reports for articular cartilage. in this study we aimed to develop a technique to decellularize bovine articular cartilage as a biological construc...

In this study we examined enhancement effects of Artemisinin plus Glucantime and shark cartilage extract, on promastigotes and amastigotes of L.infantum in in vitro condition.The toxicity of artemisinin, glucantime and shark cartilage extract on the L. infantum promastigotes and amastigote-infected macrophages was evaluated using MTT assay. The role of these drugs in inducing apoptosis in proma...

Articular cartilage, the load-bearing tissue of the joint, has limited repair and regeneration ability. The scarcity of treatment modalities for large chondral defects has motivated researchers to engineer cartilage tissue constructs that can meet the functional demands of this tissue in vivo. Cartilage tissue engineering requires 3 components: cells, scaffold, and environment. ...

a dog was presented with history of progressive generalized subcutaneous emphysema and exercise intolerance secondary to dog fight. radiographic evaluation confirmed extensive subcutaneous emphysema, pneumomediastinum and pneumoretroperitoneum. surgical exploration revealed cricoid cartilage longitudinal fracture and cricotracheal detachment. the fractured cartilage was sutured and the cricoid ...

Objective(s) Articular cartilage tissue defects cannot be repaired by the proliferation of resident chondrocytes. Autologous chondrocyte transplantation (ACT) is a relatively new therapeutic approach to cover full thickness articular cartilage defects by in vitro grown chondrocytes from the joint of a patient. Therefore, we investigated the redifferentiation capability of human chondrocytes ma...