background: despite the negative effect of fear of falling during functioning and social participation of patients with parkinson' disease, so far, only few studies have investigated its effect on the quality of life in these patients. we aimed to investigate the association between fear of falling and quality of life controlling for balance impairments based on hip and ankle strategy in d...

introduction: effective perception of fear signals is crucial for organism survival. when threated, the organism indicates defensive behaviors. methods: elevated plus–maze has high efficiency for measurement of fear behavior and is widly used for fear behavior determination. increase in two parameters percent of openarm entries (%oae) and percent of time spent in the open-arm (%oat) in the elev...

the purpose of the present study was to determine the role of medial prefrontal cortex (mpfc) dopaminergic system in fear conditioning response considering individual differences. animals were initially counterbalanced and classified based on open field test, and then were given a single infusion of the dopamine agonist, amphetamine (amph) and antagonist, clozapine (clz) into the medial prefron...

Recent advances in the field of fear learning have demonstrated that a single reminder exposure prior to extinction training can prevent the return of extinguished fear by disrupting the process of reconsolidation. These findings have however proven hard to replicate in humans. Given the significant implications of preventing the return of fear, the purpose of the present study was to further s...

mental health in adolescents is influenced by several factors. body image is one of the factors in predicting mental health. moreover, it affects social communication and creates the social anxiety. the present study is cross-sectional and correlational. the statistical population is the guidance and high school students in shiraz in 2013-2014 that 180 students include 101 girls and 79 boys wer...

We recently developed a procedure to study fear incubation, in which rats given 100 tone-shock pairings over 10 days show low fear 2 days after conditioned fear training and high fear after 30 days. Notably, fear 2 days after 10 sessions of fear conditioning is lower than fear seen 2 days after a single session of fear conditioning, suggesting that fear is suppressed. Here, we investigate the p...

Introduction: The basolateral amygdala (BLA) and infralimbic area (IL) of the medial prefrontal cortex (mPFC) are two interconnected brain structures that mediate both fear memory expression and extinction. Besides the well-known role of the BLA in the acquisition and expression of fear memory, projections from IL to BLA inhibit fear expression and have a critical role in fear extinction. Howev...