background: falciparum malaria is a severe health burden worldwide. antigen presenting cells are reported to be affected by erythrocytic stage of the parasite. malarial hemozoin (hz), a metabolite of malaria parasite, has adjuvant properties and may play a role in the induction of immune response against the parasite. objective: to determine the immunological impact of hemozoin on the capacity ...

Background Voriconazole therapy for fungal infections usually continues several years and is often administered on an outpatient basis. Maintaining the voriconazole plasma concentration in therapeutic range highly important effective therapy; however, it difficult to obtain sufficient information assess outpatients. Therefore, we developed a method simultaneously measure concentrations of its m...

background: it has been shown that zinc has an effect on physiological responses in animals and birds. on the other hand, dietary phytase in poultry results in increased availability of zinc. objectives: this study was conducted to investigate the effects of zinc oxide (zno) and escherichia coli-derived 6-phytase supplemented diets on the plasma metabolites and enzyme activities of broiler bree...

Background: Cerebral amyloid angiopathy (CAA) is one of the major causes intracerebral hemorrhage and vascular dementia in older adults. Early diagnosis will provide clinicians with an opportunity to intervene early suitable strategies, highlighting importance pre-symptomatic CAA biomarkers. Objective: Investigation related blood metabolite alterations Dutch-type hereditary mutation carriers (D...