Philip Greenland, MD, Chair; Jonathan Abrams, MD; Gerard P. Aurigemma, MD; M. Gene Bond, PhD; Luther T. Clark, MD; Michael H. Criqui, MD; John R. Crouse III, MD; Lawrence Friedman, MD; Valentin Fuster, MD, PhD; David M. Herrington, MD, MHS; Lewis H. Kuller, MD, DrPH; Paul M. Ridker, MD, MPH; William C. Roberts, MD; William Stanford, MD; Neil Stone, MD; H. Jeremy Swan, MD, PhD; Kathryn A. Tauber...

For practitioners committed to coronary risk reduction, recent clinical trial data pose a considerable challenge. Specifically, in the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS), a primary prevention trial,1 treatment with lovastatin among an apparently healthy group of individuals without traditional coronary risk factors resulted in significant reductions in fu...

Low dose aspirin is effective, safe, and economical in the secondary prevention of cardiovascular disease. We have found that only one-third of post-menopausal women with cardiovascular disease are using aspirin and that the majority of women who are using aspirin are doing so for primary prevention. Improvements in this area of medical practice are both necessary and feasible.

In this article we discuss 3 hypotheses to attempt to understand why preventive measures thus far studied with the aim of preventing (or delaying) the development of asthma have shown such disappointing results. The most likely explanation is that the development of a multifactorial disease, such as asthma, is extremely difficult, if not impossible, to prevent by eliminating only one risk facto...

Effective primary and secondary cancer prevention programmes are key to improve public health. Cervical cancer is preventable if high quality screening programmes, diagnosis and treatment are offered to female populations at high coverage. Nevertheless, it continues to be a public health problem, and screening programmes need improvements. Human papillomavirus (HPV) has been firmely established...

The objective of this paper is to study the impact of risk perception and diagnostic information on medical prevention decisions. The intertemporal preferences of individuals are represented by a model of recursive rank dependent utility, which has the advantage of allowing risk perceptions to vary over time and with health status. The main results of the paper are the following. Concerning the...

School-based programs in the United States are very limited. Other countries in the world have established programs for many years which provide comprehensive services to school-age children. In this country philosophical and professional pressures have maintained school-based programs only in the area of primary prevention. Most treatment programs involving secondary prevention are not school-...

Dyslipidemia has been recognized as an important risk-factor for the development of cardiovascular disease. The current, available therapies of dyslipidemia, their effectiveness, costs, cost-effectiveness and healthcare implications are discussed. At the present time, the lipid-lowering therapies are dominated by statins. Despite a variety of assumptions regarding modeling cardiovascular diseas...

The past few decades have witnessed an increase in the prevalence of IgE-mediated food allergy (FA). For prevention strategies to be effective, we need to understand the causative factors underpinning this rise. Genetic factors are clearly important in the development of FA, but given the dramatic increase in prevalence over a short period of human evolution, it is unlikely that FA arises throu...

Youngsters' addiction potential has made adolescence a highly sensitive and critical period of life. Educational interventions can affect addiction prevention and cooperative learning is one of the active education methods. The present study aimed to determine the effect of cooperative learning on drug addiction potential among female students. This randomized controlled cli...