Objective(s):To culture thein vitro mouse embryonic stem cells (mESCs) and to direct their  differentiation to germ-line cells; in present study we used a vector backbone containing the fusion construct Stra8-EGFP to select differentiated ES cells that entered meiosis.  Retinoic acid was used to differentiate embryonic stem cells to germ cells. Materials and Methods: A fragment of Stra8 gene pr...

in this paper, a robust integral of the sign error (rise) feedback controller is designed for a rigid-link electrically driven (rled) robot manipulator actuated by direct current dc motor in presence of parametric uncertainties and additive disturbances. rise feedback with implicitly learning capability is a continuous control method based on the lyapunov stability analysis to compensate an add...

Good similarity functions are at the heart of effective case-based reasoning. However, the similarity functions that have been designed so far have been mostly linear, weighted-sum in nature. In this paper, we explore how to handle case retrieval when the case base is nonlinear in similarity measurement, in which situation the linear similarity functions will result in the wrong solutions. Our ...

The efficiency and performance of Twin Support Vector Machines (TWSVM) is better than the traditional support vector machines when it deals with the problems. However, it also has some problems. As the same as the traditional support vector machines, its parameters are difficult to be appointed and it is not easy to select the appropriate kernel function. TWSVM generally selects the Gaussian ra...

Support Vector Machines (SVM) have demonstrated their ability in solving classification problems in an optimal way with a solid mathematical background. In this paper we improve the interpretability of SVM’s by showing that every SVM is exactly represented by a Fuzzy Rule BasedSystem, for every kernel function used. Nevertheless, this system is in some way compact in their rules and for that re...