introduction: shark cartilage has been shown to have some inhibitory effects on angiogenesis, metastasis, cell adhesion and proteolysis. patients and methods: in this study, we evaluated the effect of shark cartilage on immune response in three treatment session of 3 weeks, 6 weeks and 12 weeks on stage iii invasive ductal carcinoma patients (n=15) compared to patients treated with a starch pla...

In article number 2100315 by Robert L. Mauck and co-workers, a hyaluronic acid (HA) system is used to modify the surface of damaged cartilage. This interdigitating microenvironment enhances multi-scale mechanics degenerated cartilage, restoring response chondrocytes within. modified tissue can then be improve adhesion behavior stem cells, providing route “seal” cartilage defects. Together, this...

background : in recent years tissue engineering developed to replace or repair damaged tissues using cell and biomaterial. one of the most important fields of tissue engineering is simulation of in vivo micro environment of body tissues. this study aimed to develop culture chamber and cell biomaterial sheet engineering for the reconstruction of cartilage tissue. methods : stainless steel cultur...

BACKGROUND Cartilage tissue has limited regenerative capacity and the management of cartilage defects has always been a challenging issue. Platelet-rich plasma (PRP) has been recently been used to improve healing of cartilage defects. In the present experiment, we aimed to investigate the effects of PRP on regeneration capacity as well as survival of the cartilage grafts in a rabbit model. M...

background in recent years, there is an increasing tendency to use diced cartilage grafts in rhinoplasty surgery for improving dorsum contour irregularities. this study was designed to compare graft resorption between three techniques of diced cartilage using surgical blade, electrical grinder and grater in rabbit model. methods thirteen new zealand rabbits were divided into three groups. three...

Cartilage Repair In article number 2101127 by Lewis W. Francis, Francesca Taraballi, and co-workers, a biomimetic immune tuning scaffold is implanted in full-thickness chondral defect rabbits. The early inflammatory infiltrates changed the treated animals resulting better cartilage homeostasis at longer timepoints. This work represents first approach of reaction with bulk material to achieve re...

introduction: laryngotracheal stenosis can be caused after traumatic injuries to the neck from the subglottic larynx to the trachea. patients with laryngotracheal stenosis often need a tracheotomy and occasionally may become tracheotomy dependent. different procedures have been described for the management of these lesions. management options include techniques of endoscopic dilation, laser res...

background: recent studies have provided evidence that integrins play roles in recognition of mechanical stimuli and its translation into a cellular response. integrin signaling may be regulated by a number of mechanisms including accessory proteins such as cd98 (4f2 antigen). objectives: to determine cd98 expression by human articular chondrocytes and its involvement in human articular mechano...