BACKGROUND The lidocaine patch has been effectively used as a first-line therapy to treat neuropathic pain such as postherpetic neuralgia (PHN). OBJECTIVE To evaluate the safety and efficacy of the topical piroxicam patch as a treatment option for the treatment of PHN. METHODS Eighteen patients completed a 3-session study, applying three different patches (lidocaine, piroxicam and control) ...

Sudden severe hypotension also occurs in an otherwise stable surgery when adrenaline-containing in lidocaine is infiltrated and care must be taken when using adrenaline-containing in lidocaine because it occasionally induces several adverse reactions. We report the case of a 16-yearold man who scheduled for oral surgery in which abnormal arterial blood pressure changes occurred after adrenaline...

BACKGROUND Lidocaine-prilocaine cream (EMLA) is currently standard therapy to alleviate procedural pain in children. One of the disadvantages of lidocaine-prilocaine is the need to wait for 60 minutes for adequate skin anesthesia. Amethocaine gel (Ametop) is a new topical anesthetic that requires a shorter application time for skin anesthesia. OBJECTIVES To compare the relative efficacy and s...

Purpose: To investigate and compare the analgesic effects of nerve block anesthesia local infiltration in one-visit root canal therapy mandibular molars. 
 Methods: A total 120 patients who underwent for molars were divided into group (n = 76) 44). Lidocaine was used to anesthetize two groups. Perioperative heart rate (HR), diastolic blood pressure (DBP) systolic (SBP) determined Visual an...

OBJECTIVE To evaluate the effects of intravenously infused lidocaine on analgesia and gastrointestinal function of patients receiving laparoscopic common bile duct exploration. METHODS Seventy-eight patients with cholelithiasis were randomly divided into a treatment group and a control group (n=39) that all had laparoscopic common bile duct exploration. The treatment group was intravenously i...

OPICAL ANESTHESIA REPRESENTS A T c o m m o d y used anesthetic technique for a variety of endoscopic procedures.'4 In general, local anesthesia for endoscopy is a safe and effective procedure.g However, it has been shown that certain local anesthetics, such as tetracaine, are rapidly absorbed from the mucous membranes of the respiratory tract and can lead to severe toxic effects in man.' Thus, ...

BACKGROUND Administration of local anesthetics at body temperature has been reported to shorten the onset time of regional block; however, studies examining the effects of warmed lidocaine on the onset of epidural anesthesia are limited. Here, we ascertain whether warming lidocaine solution to body temperature shortens the time to onset of epidural anesthesia. METHODS Eighty patients were ran...

Laser– assisted permanent hair removal iscommonly performed for the treatment of unwantedhair. This procedure is usually associated withpain and pain reduction has an important role inthe success of this treatment. A common methodof reducing pain is to use topical analgesics . Amixture of lidocaine and prilocaine (EMLA) is acommonly used and very effective topical anesthetic.Another agent is di...

The World Health Organization designates lidocaine as an essential medicine in healthcare, greatly increasing the probability of human exposure. Its use has been associated with ROS generation and neurotoxicity. Physiological and metabolomic alterations, and genetics leading to the clinically observed adverse effects have not been temporally characterized. To study alterations that may lead to ...