Rhabdomyosarcoma (RMS) is the commonest soft sarcoma in kids, with alveolar and embryonal variants distinguishable by histopathology and, more significantly, molecular biology. RMS occurs intermittently a substantial proportion of cases without predisposing condition. Nevertheless, it well established that certain hereditary factors enhance likelihood developing RMS. Beckwith–Wiedemann syndrome...

congenital or neonatal rhabdomyosarcoma is a rare entity, usually presenting as masses in the head and neck region as well as genitourinary tract. the embryonal variant is the most common type occurring in infancy. this is a case of congenital rhabdomyosarcoma with a huge forearm mass, with metastatic discrete nodules in the soft tissues of the neck and scapular region, resembling a ‘blueberry ...

Alveolar rhabdomyosarcoma comprises a rare highly malignant tumor presumed to be associated with skeletal muscle lineage in children. The hallmark of the majority of alveolar rhabdomyosarcoma is a chromosomal translocation that generates the PAX3-FOXO1 fusion protein, which is an oncogenic transcription factor responsible for the development of the malignant phenotype of this tumor. Alveolar rh...

BACKGROUND Rhabdomyosarcoma is the most common soft tissue sarcoma in childhood and has a poor prognosis. Here we assessed the capability of ex vivo expanded cytokine-induced killer cells to lyse both alveolar and embryonic rhabdomyosarcoma cell lines and investigated the mechanisms involved. DESIGN AND METHODS Peripheral blood mononuclear cells from six healthy donors were used to generate a...

Replication restricted oncolytic viruses such as multimutated herpes simplex virus type 1 (HSV-1) G207 represent a novel and attractive approach for cancer therapy, including pediatric solid tumors. Rhabdomyosarcoma is the most common soft-tissue sarcoma of childhood and is often diagnosed already as an advanced disseminated disease. Despite aggressive therapeutic approaches, the prognosis for ...

This is a picture review of a case of orbital rhabdomyosarcoma. The course of patients diagnosis, treatment and outcome is briefly presented.

Infants younger than one year of age with Rhabdomyosarcoma appear to have worse prognosis compared to older children due partly to high rates of local failure. We report a 4 months old infant with orbital rhabdomyosarcoma with poor outcome. Reluctance to use aggressive local control measures and suboptimal chemotherapy dosing are significant contributory factors. Call is made for need for more ...

Introduction. The most common sarcoma of childhood is rhabdomyosarcoma, approximately 35% of all paediatric rhabdomyosarcomas occur in the head and neck. Case Report. A 3-year-old girl referred to our clinic due to serosanguineous purulent discharge from her right ear. After paraclinical and pathologic evaluation it was diagnosed as embryonic rhabdomyosarcoma. Conclusions. In all children with ...

of primary cardiac tumors are benign tumors, such as myxoma.2) According to Prichard,3) the incidence of the cardiac rhabdomyosarcoma is lower than that of angiosarcoma, and nearly the same or slightly higher than that of other fibrosarcoma, reticulum cell sarcoma, and lymphosarcoma. We experienced an extremely rare case of rhabdomyosarcoma, which replaced the atrioventricular (A-V) node comple...

Rhabdomyosarcoma is highly aggressive malignant form of mesenchymal tumor arising from skeletal muscle cells rhabdomyoblast, that have failed to fully differenciate. It most commonly seen in the children before 12 year age. Primary spinal rhabdomyosarcoma very rare. A 2 old girl presented with mass over right upper back and inability move lower limb. Patient underwent dorsal laminectomy excisio...