Using ideas from an article of P. Bieliavsky, M. Rooman and Ph. Spindel on BTZ black holes, I construct a family of interesting examples of quasi-Poisson actions as defined by A. Alekseev and Y. Kosmann-Schwarzbach. As an application, I obtain a genuine Poisson structure on SL(2, R) which induces a Poisson structure on a BTZ black hole.

A novel cell-targeting, pH-sensitive polymeric carrier was employed in this study for delivery of the anticancer drug bortezomib (BTZ) to cancer cells. Our strategy is based on facile conjugation of BTZ to catechol-containing polymeric carriers that are designed to be taken up selectively by cancer cells through cell surface receptor-mediated mechanisms. The polymer used as a building block in ...

It is shown that a massless scalar probe reveals a universal near-horizon conformal structure for a wide class of black holes, including the BTZ. The central charge of the corresponding Virasoro algebra contains information about the black hole. With a suitable quantization condition on the central charge, the CFT associated with the black hole in our approach is consistent with the recent obse...

OBJECTIVE To investigate the effects of CAL-101, particularly when combined with bortezomib (BTZ) on mantle cell lymphoma (MCL) cells, and to explore its relative mechanisms. METHODS MTT assay was applied to detect the inhibitory effects of different concentrations of CAL-101. MCL cells were divided into four groups: control group, CAL-101 group, BTZ group, and CAL-101/BTZ group. The expressi...

Bortezomib (BTZ) is a proteasome inhibitor approved in the treatment of multiple myeloma (MM). Bortezomib-induced peripheral neuropathy (BIPN) is an unpredictable dose-limiting adverse event in one-third of patients. In the present study, 58 relapsed/refractory MM patients treated with BTZ were analyzed. The study's aim was to compare BIPN incidence and severity between both groups and to ident...

New therapies for glioblastoma (GBM) are needed, as five-year survival is <10%. The proteasome inhibitor marizomib (MRZ) has inhibitory and death-inducing properties unique from previous inhibitors such as bortezomib (BTZ), and has not been well examined in GBM. We evaluated the mechanism of death and in vivo properties of MRZ in GBM. The activation kinetics of initiator caspases 2, 8, and 9 we...

Bortezomib (BTZ), a proteasome inhibitor, is the first proteasome inhibitor to be used in clinical practice. Here we investigated the mechanisms underlying acquired bortezomib resistance in hepatocellular carcinoma (HCC) cells. Using stepwise selection, we established two acquired bortezomib-resistant HCC cell lines, a bortezomib-resistant HepG2 cell line (HepG2/BTZ) and bortezomib-resistant Hu...

We investigate solutions of new massive gravity with two commuting Killing vectors, one of which is null, with a special emphasis on black hole solutions. Besides extreme BTZ black holes and, for a special value of the coupling constant, massless null warped black holes, we also obtain for a critical coupling a family of massive “log” black holes. These are asymptotic to the extreme BTZ black h...

The emission rate of fermions from 2+1 dimensional BTZ black holes is shown to have a form which can be reproduced from a conformal field theory at finite temperature. The rate obtained for fermions is identical to the rate of non-minimally coupled fermions emitted from a five dimensional black hole, whose near horizon geometry is BTZ × M , where M is a compact manifold. 04.60.-m,04.62.+v,04.70...

We extend our recent discussion of four-dimensional black holes bound to a two-brane to include a negative cosmological constant on the brane. We find that for large masses, the solutions are precisely BTZ black holes on the brane, and BTZ ‘black strings’ in the bulk. For smaller masses, there are localized black holes which look like BTZ with corrections that fall off exponentially. We compute...