on the basis of preliminary in vitro screening tests, a competent strain of pantoea agglomerans ena1 (p. agg. ena1) recovered from soybean nodule was evaluated for its antagonistic activity against macrophomina phaseolina causal agent of charcoal rot of soybean. the results of various in vitro assays showed that p. agg. ena1 is capable of exerting strong antagonistic effect against m. phaseolin...

objective(s): the object of the study is to examine the effects of δ9-tetrahydrocannabinol (thc) against oxidative stress in the blood and excretion of thc metabolites in urine of type 2 diabetic rats. materials and methods: the control (n=8), thc control (n=6), diabetes (n=8) and diabetes + thc (n=7) groups were created. type 2 diabetes was induced by nicotinamide (na, 85 mg/kg) + streptozotoc...

BACKGROUND Many epidemiologic studies are using metabolomics to discover markers of carcinogenesis. However, limited data are available on the influence of pre-analytic blood collection factors on metabolite measurement. METHODS We quantified 166 metabolites in archived plasma from 423 Health Professionals Follow-up Study and Nurses' Health Study participants using liquid chromatography-tande...

BACKGROUND AND AIM The immunosuppressive properties of 6-mercaptopurine and its parent compound azathioprine are mediated by their intracellular metabolism into active 6-thioguanine (6-TG) metabolites. Measurement of erythrocyte 6-TG metabolite levels has been proposed as a useful clinical tool for assessing treatment efficacy in patients with inflammatory bowel disease (IBD). AIM The purpose...

UNLABELLED (11)C-meta-hydroxyephedrine ((11)C-HED) kinetics in the myocardium can be quantified using a single-tissue-compartment model together with a metabolite-corrected arterial blood sampler input function (BSIF). The need for arterial blood sampling, however, limits clinical applicability. The purpose of this study was to investigate the feasibility of replacing arterial sampling with ima...