In order to enhance the charge balance of organic near infrared (NIR) electroluminescent devices, an ancillary ligand pic-SCz which was covalently linking bipolar group SCz (composed PS (S) and tBuCz (Cz)) pic (SCz=3,6-di-tert-butyl-9-(4-(phenylsulfonyl)phenyl)-9H-carbazole; = phenyl sulfone; 3,6-di-tert-butylcarbazole; pic= 2-picolinic acid) developed for iridium (III) complex (TPA-BTz-Iq)2Ir(...

We study aspects of the propagation of strings on BTZ black holes. After performing a careful analysis of the global spacetime structure of generic BTZ black holes, and its relation to the geometry of the SL(2, R) group manifold, we focus on the simplest case of the massless BTZ black hole. We study the SL(2, R) Wess-Zumino-Witten model in the worldsheet minisuperspace limit, taking into accoun...

We study the wave equation for a massive scalar in three-dimensional AdS-black hole spacetimes to understand the unitarity issues in a semiclassical way. Here we introduce four interesting spacetimes: the non-rotating BTZ black hole (NBTZ), pure AdS spacetime (PADS), massless BTZ black hole (MBTZ), and extremal BTZ black hole (EBTZ). Our method is based on the potential analysis and solving the...

The in vitro activity of PA-824 and BTZ043 against 30 Nocardia brasiliensis isolates was tested. The MIC(50) and MIC(90) values for PA-824 were both >64 μg/ml. The same values for BTZ043 were 0.125 and 0.250 μg/ml. Given the MIC values for benzothiazinone (BTZ) compounds, we consider them good candidates to be tested in vivo against N. brasiliensis.

Abdominal aortic aneurysm (AAA) is a leading cause of sudden death in aged people. Activation of ubiquitin proteasome system (UPS) plays a critical role in the protein quality control and various diseases. However, the functional role of UPS in AAA formation remains unclear. In this study, we found that the proteasome activities and subunit expressions in AAA tissues from human and angiotensin ...

This study reports on an intelligent composite hydrogel with both pH-dependent drug release in a cancer environment and heat generation based on NIR laser exposure, for the combined application of photothermal therapy (PTT) and multidrug chemotherapy. For the first time in the literature, Dopamine nanoparticle (DP) was incorporated as a highly effective photothermal agent as well as anticancer ...

The (R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl-boronic acid, bortezomib (BTZ), which binds the 20S proteasome subunit and causes a large inhibition of its activity, is a peptidomimetic boronic drug mainly used for the treatment of multiple myeloma. Commercial BTZ, stabilized as mannitol derivative, has been investigated under the common conditions of the clinical u...

We investigate whether or not the Hawking-Page phase transition is possible to occur in three dimensions. Starting with the simplest class of LanczosLovelock action, thermodynamic behavior of all AdS-type black holes without charge falls into two classes: Schwarzschild-AdS black holes in even dimensions and Chern-Simons black holes in odd dimensions. The former class can provide the Hawking-Pag...

The effects of spacetime quantization on black hole and big bang/big crunch singularities can be studied using new tools from (2+1)dimensional quantum gravity. I investigate effects of spacetime quantization on singularities of the (2+1)-dimensional BTZ black hole and the (2+1)-dimensional torus universe. Hosoya has considered the BTZ black hole, and using a “quantum generalized affine paramete...

We investigate the connection between the BTZ black holes and the near-horizon geometry of higher-dimensional black holes. Under mild conditions, we show that (i) if a black hole has a global structure of the Reissner-Nordstrom black hole type, its near-horizon geometry is AdS2 times a sphere, and further (ii) if such a black hole is obtained from a boosted black string by dimensional reduction...