introduction lidocaine plus epinephrine is the most common anesthetic drug used in dentistry which has important cardiovascular side-effects like increase in blood pressure and cardiac arrhythmia. the goal of this study was to evaluat cardiovascular effects of one cartridge of 2% lidocaine + 1:80000 epinephrine. methods and materials 60 cases without any systemic diseases who had been admitted ...

BACKGROUND Postoperative sore throat and other airway morbidities are common and troublesome after endotracheal tube intubation general anesthesia (ETGA). We propose lidocaine as endotracheal tube (ETT) cuff inflation media to reduce the postintubation-related emergence phenomenon. METHODS We searched PubMed, EMBASE, and Cochrane databases systematically for randomized controlled trials (RCTs...

background: recent studies have indicated potential of saffron for applying in a wide variety of diseases such as psychiatric and neurologic disorders. the concurrent use of saffron with ssris can lead to reducing the dose of ssris. saffron at a dose of 200 mg may change some hematological and biochemical parameters. objective: the goal of this trial was to assess the safety of concomitant admi...

background higher life expectancy and increased ischemic heart disease (ihd) have resulted in increasing number of the elderly patients undergoing cardiac surgeries. age along with many other comorbidities influence the outcome of major surgeries in the elderly patients; hence, case selection before major surgeries is challenging. objectives the pure effect of age after adjusting for other majo...

Distal radius fractures are the most common of upper limb. It is a fracture in elderly and indiction an osteosynthesis by locked plate often posed view osteopenia. Surgical fixation distal under local anesthesia with patient wide awake without tourniquet allows intraoperative testing stability active mobilization. This technique people extensive comorbidities to avoid adverse effects commonly a...

Prilocaine and lidocaine are classified as amide-type local anesthetics for which serious adverse effects include methemoglobinemia. Although the hydrolyzed metabolites of prilocaine (o-toluidine) and lidocaine (2,6-xylidine) have been suspected to induce methemoglobinemia, the metabolic enzymes that are involved remain uncharacterized. In the present study, we aimed to identify the human enzym...

BACKGROUND The alpha(2)-adrenoceptor agonist clonidine is used in combination with lidocaine for anaesthesia. Lidocaine inhibits axonal transport and neurite growth, whereas alpha(2)-adrenoceptor agonists have neurotrophic effects. Here we have investigated whether clonidine reduces lidocaine-induced inhibition of axonal transport in cultured mouse dorsal root ganglion neurones. METHODS Axona...

conclusions despite the relatively high level of knowledge in the context of the general principles of a diet to prevent ramadan-related complications, practical training in regard to the amounts of nutrients associated with ramadan-related complications is both necessary and recommended. background ramadan fasting is associated with some lifestyle changes. a lack of nutritional needs knowledge...

BACKGROUND Systemic sclerosis (scleroderma; SSc) is an orphan disease with the highest case-specific mortality of any connective-tissue disease. Excessive collagen deposit in affected tissues is a key for the disease's pathogenesis and comprises most of the clinical manifestations. Lidocaine seems to be an alternative treatment for scleroderma considering that: a) the patient's having excessive...