145 spatial and temporal characteristics of magnetic reconnection will fuel the sometimes heated debate over what the phenomenon is like and what it can do. With the launch of NASA’s STEREO mission, expected later this year, larger baselines will become available, and there is hope that the study of solar-wind reconnection can be extended to much larger scales. At the smallest scales, NASA’s Ma...

Background The problem of malignant hyperthermia (MH) was awaken in Russia in 2012, when 3 y.o. girl died in private hospital in Saint Petersburg. MH is well known, but well forgotten by most of anaesthesiologists in Russia since we have a lack of diagnostic and treatment tools. Even if MH crisis takes place we have no specific treatment at the moment and a few opportunities for diagnosing MH s...

begun to provide a comprehensive picture of the hereditary information required for various forms of life. But what do all the genes so identified do to warrant their existence? In the unicellular yeast Saccharomyces cerevisiae, for example, all predicted genes have been deleted,and the resulting strains subjected to a battery of analyses. These genome-wide studies have shown that only about 19...

BACKGROUND Comorbid depression is common among adults with painful osteoarthritis (OA). We evaluated the relationship between depressed mood and receipt of mental health (MH) care services. METHODS In a cohort with OA, annual interviews assessed comorbidity, arthritis severity, and MH (SF-36 mental health score). Surveys were linked to administrative health databases to identify mental health...

BACKGROUND AND OBJECTIVES Malignant hyperthermia (MH) is a pharmacogenetic disease that causes abnormal hypermetabolic reaction to halogenated anesthetics and/or depolarizing muscle relaxants. In Brazil, there is a hotline telephone service for MH since 1991, available 24 hours a day in São Paulo. This article analyzes the activity of the Brazilian hotline service for MH in 2009. METHODS Pros...

Malignant Hyperthermia (MH) is a rare genetic disease. However, it is devastating when it occurs in a patient. MH is usually triggered by inhalational anesthetics and/or depolarizing muscle relaxants. Public awareness of MH has increased with the presentation of an episode on the television program, “House”, and the availability of web-based information. For over 20 years, the MH susceptible pi...

Survival from a malignant hyperthermia (MH) crisis is highly dependent on early recognition and prompt action. MH crises are very rare and an increasing use of total i.v. anaesthesia is likely to make it even rarer, leading to the potential risk of reduced awareness of MH. In addition, dantrolene, the cornerstone of successful MH treatment, is unavailable in large areas around the world thereby...

In this article, we explored 1) the extent of mental health (MH) service use by American Red Cross disaster relief workers, both before (lifetime) and 1 year after the September 11, 2001 terrorist attacks, and 2) demographic, disaster and MH variables predicting (1-year) post-September 11 MH service use in this population. A sample of 3015 Red Cross disaster workers was surveyed 1 year after th...

BACKGROUND/AIMS Mucosal healing (MH) is a proposed therapeutic goal for patients with ulcerative colitis (UC). Whether MH is the final goal for UC, however, remains under debate. Therefore, to elucidate clinical variables predicting relapse after MH in UC could be useful for establishing further therapeutic strategy. The aim of this study is to evaluate the predictive variables for relapse in U...

BACKGROUND For more than 30 yr, the in vitro contracture test (IVCT) was the only appropriate diagnostic tool for malignant hyperthermia (MH). After the introduction of molecular genetics into MH research, guidelines for molecular genetic diagnosis of MH susceptibility were published. The aim of this study was to establish applicability of the guidelines, sensitivity, and specificity of genetic...