نتایج جستجو برای: parafascicular nucleus

تعداد نتایج: 112070  

Journal: :Neuroscience 2009
J A Beatty E L Sylwestrak C L Cox

The lateral parafascicular nucleus (lPf) is a member of the intralaminar thalamic nuclei, a collection of nuclei that characteristically provides widespread projections to the neocortex and basal ganglia and is associated with arousal, sensory, and motor functions. Recently, lPf neurons have been shown to possess different characteristics than other cortical-projecting thalamic relay neurons. W...

2017
Esmaeal Tamaddonfard Amir Erfanparast

The parafascicular nucleus (PFN) of thalamus, as a supraspinal structure, has an important role in processing of nociceptive information. In addition, μ-opioid receptor contributes to supraspinal modulation of nociception. In the present study, the effects of microinjection of naloxone (a non-specific opioid-receptor antagonist) and naloxonazine (a specific μ-opioid receptor antagonist) were in...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1987
J M Trugman G F Wooten

The relative roles of D1 and D2 dopamine receptor stimulation in mediating the antiparkinsonian effects of dopaminergic drugs remain unclear. To determine the functional metabolic consequences of selective dopamine receptor stimulation, we used 2-deoxyglucose (2-DG) autoradiography to examine the effects of the D1 agonist SKF-38393 and the D2 agonist LY-171555 on regional cerebral glucose utili...

2010
C. D. Metzger U. Eckert J. Steiner A. Sartorius J. E. Buchmann J. Stadler C. Tempelmann O. Speck B. Bogerts B. Abler M. Walter

Thalamocortical loops, connecting functionally segregated, higher order cortical regions, and basal ganglia, have been proposed not only for well described motor and sensory regions, but also for limbic and prefrontal areas relevant for affective and cognitive processes. These functions are, however, more specific to humans, rendering most invasive neuroanatomical approaches impossible and inte...

Journal: :The Journal of comparative neurology 1997
M Sidibé M D Bevan J P Bolam Y Smith

The objectives of this study were, on one hand, to better understand how the segregated functional pathways from the cerebral cortex through the striatopallidal complex emerged in the projections to the thalamus and, on the other hand, to compare the ultrastructure and synaptic organization of the pallidal efferents to the ventrolateral (VL) and centromedian (CM) thalamic nuclei in primates. Th...

Journal: :Journal of neuropathology and experimental neurology 2006
William L Maxwell Mary Anne MacKinnon Douglas H Smith Tracy K McIntosh David I Graham

Paraffin-embedded blocks from the thalamus of 9 control patients, 9 moderately disabled, 12 severely disabled, and 10 vegetative head-injured patients assessed using the Glasgow Outcome Scale and identified from the Department of Neuropathology archive. Neurons, astrocytes, macrophages, and activated microglia were differentiated by Luxol fast blue/cresyl violet, GFAP, CD68, and CR3/43 staining...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2011
Shigeki Kato Masahito Kuramochi Kenta Kobayashi Ryoji Fukabori Kana Okada Motokazu Uchigashima Masahiko Watanabe Yuji Tsutsui Kazuto Kobayashi

The dorsal striatum receives converging excitatory inputs from diverse brain regions, including the cerebral cortex and the intralaminar/midline thalamic nuclei, and mediates learning processes contributing to instrumental motor actions. However, the roles of each striatal input pathway in these learning processes remain uncertain. We developed a novel strategy to target specific neural pathway...

Journal: :Neuroscience 1992
S R Lapper J P Bolam

Evidence derived from many experimental approaches indicates that cholinergic neurons in the dorsal striatum (caudate-putamen) are responsive to excitatory amino acids. Furthermore, evidence from physiological experiments indicate that the excitatory input is derived from the cortex and/or the thalamus. The object of the present experiment was to anatomically test whether cholinergic neurons re...

2016
Hugh P. Sims-Williams Shazia Javed Anthony E. Pickering Nikunj K. Patel

BACKGROUND Several deep brain stimulation (DBS) targets have been explored for the alleviation of trigeminal anaesthesia dolorosa. We aimed to characterise the analgesia produced from the periaqueductal grey (PAG) and centromedian-parafascicular (CmPf) nucleus using a within-subject design. METHOD We report a case series of 3 subjects implanted with PAG and CmPf DBS systems for the treatment ...

2014
Yong-Hua Li Jia-Jia Li Qin-Chi Lu Hai-Qing Gong Pei-Ji Liang Pu-Ming Zhang

Studies have suggested that thalamus is involved in temporal lobe epilepsy, but the role of thalamus is still unclear. We obtained local filed potentials (LFPs) and single-unit activities from CA1 of hippocampus and parafascicular nucleus of thalamus during the development of epileptic seizures induced by pilocarpine in mice. Two measures, redundancy and directionality index, were used to analy...

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