In the past there has been considerable variation in the way thyroid cytology was reported by pathologists. As the need for improving patient care increased to include more conservative surgical procedures for the management of thyroid lesions, there was a need for a standardized reporting format. This had to be reproducible and universal so that the implications of the reporting categories wer...

In the past there has been considerable variation in the way thyroid cytology was reported by pathologists. As the need for improving patient care increased to include more conservative surgical procedures for the management of thyroid lesions, there was a need for a standardized reporting format. This had to be reproducible and universal so that the implications of the reporting categories wer...

doi: 10.1111/j.1365-3083.2006.01767.x Ghost Lab, l.aboratorv of Cellular and Molecular Immunology, Natienat lnstitute of Alterqv and lnfectious Diseases, National lnstitutes ofHealth, Bethesda, MD, USA Received 22 Morch 2006; Accepted in revisedterm 8 April 2006 Com-spcncence la: DI' K. Abdi, Ghost Lab, l.aboratorv of Cellular and Molecular Immunology, National lnstitute of Allergy ...

Women with hereditary non-polyposis colorectal cancer (HNPCC)/Lynch syndrome have a high risk for endometrial cancer (EC) and frequently present with a gynaecological cancer as their first or sentinel malignancy. Identification of these patients is important given their personal and family risk for synchronous and metachronous tumours. Modalities to detect ECs for the possibility of HNPCC inclu...

Factor VIII inhibitors are produced during or after coagulation factor VIII (FVIII) therapy in hemophilia A patients. These inhibitors are usually detected by a modified Bethesda assay or an enzyme-linked immunosorbent assay (ELISA). In this study, we used the Bethesda assay to determine the incidence of FVIII inhibitors in 75 fresh plasma samples obtained from 50 hemophilia A patients, and the...

OBJECTIVE To review the adequacy and diagnostic categories of the Bethesda system for reporting Pap test results (cervicovaginal cytology) and summarize management options. QUALITY OF EVIDENCE The latest research evidence and guidelines from both international and Canadian sources are reviewed. With a few exceptions, good evidence supports particular management approaches for each adequacy stat...

Thyroid nodules are commonly encountered in clinical practice. Although the overwhelming majority of them turn out to be benign, the small subset of cancerous nodules needs to be accurately identified for optimal and timely surgical management. Fine-needle aspiration has proven to be the most valuable diagnostic modality for pre-operative distinction of benign from malignant nodules. The recent...

Center for Neuroscience and Regenerative Medicine, Henry M. Jackson Foundation, Bethesda, MD, United States, Radiology and Radiological Sciences, Uniformed Services University of the Health Sciences, Bethesda, MD, United States, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, United States, Center for Neuroscience and...

320. VRE Colonization and Infection at the NIH Clinical Center (NIHCC) Heather Y. Hughes, MD; Robin T. Odom, MS; Angela V. Michelin, MPH; Evan S. Snitkin, PhD; David K. Henderson, MD, FIDSA; Tara N. Palmore, MD; National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD; Hospital Epidemiology Service, National Institutes of Health Clinical Center, NIH, Bethesda, MD; National Human...

A decrease in inhibitor titer has been reported in some patients with acquired factor VIII inhibitors treated with intravenous gammaglobulin (IGIV). We have conducted a prospective, multicenter study of high-dose IGIV in treatment of this disorder to determine efficacy. Nineteen patients received induction therapy with IGIV, 1,000 mg/kg x 2 consecutive days or 400 mg/kg x 5 consecutive days, fo...