نتایج جستجو برای: ups سری

تعداد نتایج: 26292  

Journal: :journal of fasting and health 0
konstantinos havenetidis faculty of physical and cultural education hellenic army academy

background and objectives: given the limited number of studies on ramadan fasting and military performance, we conducted this study to identify the effect of ramadan fasting on physical fitness performances in army cadets. methods: twenty healthy males were randomly selected from a larger sample group. the subjects were divided into fasting (n=10) and non-fasting (n=10) groups. they performed v...

Journal: :The EMBO journal 2010
Yasushi Tamura Miho Iijima Hiromi Sesaki

Ups1p, Ups2p, and Ups3p are three homologous proteins that control phospholipid metabolism in the mitochondrial intermembrane space (IMS). The Ups proteins are atypical IMS proteins in that they lack the two major IMS-targeting signals, bipartite presequences and cysteine motifs. Here, we show that Ups protein import is mediated by another IMS protein, Mdm35p. In vitro import assays show that i...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2010
Zaira Ortega Miguel Díaz-Hernández Christa J Maynard Félix Hernández Nico P Dantuma José J Lucas

The presence of intracellular ubiquitylated inclusions in neurodegenerative disorders and the role of the ubiquitin/proteasome system (UPS) in degrading abnormal hazardous proteins have given rise to the hypothesis that UPS-impairment underlies neurodegenerative processes. However, this remains controversial for polyglutamine disorders such as Huntington disease (HD). Whereas studies in cellula...

Journal: : 2023

شاخص سطح برگ استخراج‌شده (LAI) از تصاویر سنجش دور پارامتر مهمی، به‌منظور مدل‌سازی مکانی تولید پوشش گیاهی، محسوب می‌شود. معمولاً شاخص‌های گیاهی که با بازتاب طول موج‌های قرمز و مادون نزدیک محاسبه می‌شوند، در برآورد LAI استفاده روش‌های آماری، به‌کار می‌روند اما بسیاری این شاخص‌ها مقادیر متفاوت به اشباع می‌رسند. برای رفع محدودیت، محدودة لبة شده است؛ بنابراین، باید قابلیت داده‌های دور، ذرت علوفه‌ای، ...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2008
Suzanne Tydlacka Chuan-En Wang Xuejun Wang Shihua Li Xiao-Jiang Li

A variety of neurological disorders and polyglutamine (polyQ) diseases are caused by misfolded proteins. The common feature of these diseases is late-onset cellular degeneration that selectively affects neurons in distinct brain regions. polyQ diseases, including Huntington's disease (HD), present a clear case of selective neurodegeneration caused by polyQ expansion-induced protein misfolding, ...

Journal: :FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005
Asangi R K Kumarapeli Kathleen M Horak Joseph W Glasford Jie Li Quanhai Chen Jinbao Liu Hanqiao Zheng Xuejun Wang

Ubiquitin-proteasome system (UPS) mediated proteolysis is responsible for the degradation of majority of cellular proteins, thereby playing essential roles in maintaining cellular homeostasis and regulating a number of cellular functions. UPS dysfunction was implicated in the pathogenesis of numerous disorders, including neurodegenerative disease, muscular dystrophy, and a subset of cardiomyopa...

2015
Annael Brunet Catherine Tardin Laurence Salom'e Philippe Rousseau Nicolas Destainville Manoel Manghi

Annaël Brunet, 2, 3, 4 Catherine Tardin, 2 Laurence Salomé, 2 Philippe Rousseau, 6 Nicolas Destainville, 4 and Manoel Manghi 4 Institut de Pharmacologie et Biologie Structurale, UMR CNRS-UPS 5089, 31062 Toulouse, France Université de Toulouse, UPS, Institut de Pharmacologie et Biologie Structurale, 31062 Toulouse, France Université de Toulouse, UPS, Laboratoire de Physique Théorique (IRSAMC), 3...

Journal: :Pharmacological reviews 2007
Jason J Yi Michael D Ehlers

Alterations in cellular structure and synapse composition are central to proper nervous system function. Recent work has identified the ubiquitin-proteasome system (UPS) as a key regulator of neuronal biology. The UPS is essential for the growth and development of immature neurons and is a critical mediator of synaptic adaptability in mature neurons. Furthermore, proteinaceous deposits that acc...

Journal: :Psychosomatic medicine 2004
Cornelis G Kooiman Jan H Bolk Harry G M Rooijmans Rutger W Trijsburg

BACKGROUND Alexithymia is thought to be associated with the development of medically unexplained physical symptoms (UPS). So far little research has been published on alexithymia as a risk factor for the persistence of UPS. OBJECTIVE To determine the clinical outcome in UPS patients and to study the relative importance of alexithymia in predicting that outcome. METHODS A follow-up study was...

2017
Ganapathy van Samkar Henning Hermanns Philipp Lirk Markus W. Hollmann Markus F. Stevens

Postoperative epidural analgesia often needs rate readjustment using top-ups. Patient-controlled epidural analgesia (PCEA) is said to reduce the requirement of epidural top-ups when compared to continuous epidural analgesia (CEA). We compared CEA and PCEA in major thoracic and abdominal surgery, in a cohort study. The primary endpoint was the required number of epidural top-ups. Secondary endpo...

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