background: osteoporosis, or porous bone, is a disease characterized by low bone mass density (bmd) and structural deterioration of bone tissue, leading to bone fragility and increased risk of hip, spine, and wrist fractures. there are numerous risk factors for osteoporosis. while many of these factors are non-genetic in nature, there is a definite genetic component responsible for this conditi...

purpose oligo/amenorrhea, as a part of the female athlete triad has adverse effects on the athlete's bone mineral density (bmd) and cardiovascular system. hypoestrogenism, due to suppression of hypothalamus-pituitary axis (hpa) as a result of energy imbalance, is the possible cause of the triad. this study was designed based on following up and reassessment of elite female athletes who were dia...

background: β-thalassemia major is a hereditary life threatening anemia which requires regular blood transfusion. clinical symptoms of the disease are growth retardation, pallor, jaundice and skeletal alternations. the variety of bone disease in thalassemia major is manifested by diffuse bone pain or deformity, spontaneous and pathologic fractures and osteopenia or osteoporosis. this study aime...

introduction : deproteinized bovine bone mineral (bio-oss) is a xenogenic bone substitute, widely used in maxillofacial bone regeneration. the aim of this in vitro study was to investigate its influence on the growth behavior of human osteosarcoma cell line, saos-2 culture, and compare it with the physiologic dose of dexamethasone, an inductive factor for osteoblasts. materials and methods: hum...

BACKGROUND Cancellous bone from patients with osteoarthritis (OA) has been reported to be undermineralised and that from patients with osteoporosis (OP) is more liable to fracture. Changes in the mineral component might be implicated in these processes. OBJECTIVES To investigate the thermal stability and the mineral structure of cancellous bone from femoral heads of patients with either OA or...

In species with repeated bouts of reproduction, a female's ability to retain sufficient tissue for self-maintenance is essential to her survival and capacity for future reproduction. Loss of bone mineral content results in bone fragility and the possibility of reduced survival, so females should guard against the overuse of their bone mineral during reproduction. Given these constraints, I pred...

CONTEXT Calcium Nephrolithiasis is a multifactorial disease; in its pathophysiology is involved various minerals and metabolic factors that may be altered, including bone and phosphor-calcium metabolism. OBJECTIVE To establish the scientific evidence and demonstrate the relationship between calcium nephrolithiasis and bone mineral density loss, through the use of bone turnover markers, serum ...

BACKGROUND Helicobacter pylori (H. pylori) infection may cause systemic inflammation and increase the production of tumor necrosis factor-α, interleukin-1, and interleukin-6. Unfortunately, bone mineral density also may be affected by these cytokines. This study aimed to evaluate the association between bone mineral density and H. pylori infection. METHODS A cross-sectional study evaluated 1,...

OBJECTIVES A longitudinal study was conducted to investigate the relationships of the change in radius bone mineral density for seven years with lifestyle, body measurement data and laboratory data. METHODS The subjects of this study were 191 female employees working in an LSI manufacturing factory in Japan. Bone mineral density was measured on the radius of their nondominant side using DXA (...

BACKGROUND Persons with unilateral, lower-extremity amputation sometimes develop osteoarthritis in the intact limb. The purpose of this study was to investigate gait mechanics and bone mineral density in unilateral, trans-tibial amputees to test the hypotheses that the intact limb knee and hip will have larger frontal plane net joint moments and bone mineral density than the prosthetic side and...