this study was carried out to analyze certain epidemiological variations in iranian patients with colorectal cancer. (crc): from march 1981 up to march 1993, 103 patients were analyzed retrospectively for age, gender, marital state, job, nutritional habits, presenting symptoms and histopathological features. most of the patients with colorectal cancer were male, age range 20-75 (mean 56), 25.4 ...

background: colorectal cancer (crc) is the second cause of cancer-related deaths worldwide. there have been several studies reporting the proximal tumor shift, especially in western countries. in the present study, we investigated the clinicopathologic and anatomical distributions of colorectal tumors in iranian crc patients. materials and methods: in this retrospective cohort study,258 patient...

aim : the aim of this study was to provide quantitative estimations of the burden of death in term of years of life lost (yll) due to colorectal cancer (crc) in iran and a temporal trend analysis. background : colorectal cancer is the third most common cause of cancer-related deaths in the world. yll is a tool for quantifying the burden of disease according to mortality rates. the aim of this s...

Objective(s): Ten-eleven translocation (TET) family members have been shown to be involved in the development of many tumors. However, the biological role of the TET family and its mechanism of action in colorectal carcinogenesis and progression remain poorly understood. Materials and Methods:We measured the expression levels of TET family members in colorectal cancer (CRC) specimens, in the c...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : there is a lack of data on familial aggregation of colorectal cancer (crc) in iran. we aimed to determine the frequency of hereditary nonpolyposis colorectal cancer (hnpcc) and familial colorectal cancer (fcc) and to determine the frequency of extracolonic cancers in these families in isfahan. methods : we rev...

abstract: colorectal cancer (crc) is the third most common cancer in men and the second most common cancer in women worldwide. both genetic and epigenetic alterations are common in crc and are the driving force of tumorigenesis. chromosomal instability, microsatellite instability and cpg island methylator phenotype pathways are responsible for genetic instability in colorectal cancer. chromosom...

background: there are no data on familial aggregation of colorectal cancer (crc) in northeastern iran. the aim of this study was to determine the prevalence of early-onset crc and patients suspected for hereditary non-polyposis colorectal cancer (hnpcc) based on the clinical criteria in this area. materials and methods: documents were collected from two hospitals in mashhad regarding 326 inpati...

background colorectal cancer (crc) is the second most common malignancy in the world.  however, its mortality rate can be reduced if diagnosed early. p33 ing1b is a tumor suppressor protein, which plays a role in growth control and apoptosis. suppression of p33 ing1b is associated with the loss of cellular growth control. however, p33 ing1b expression in crc and its correlations with clinicopat...