Multiorgan failure remains one of the leading causes of late morbidity and mortality after severe trauma. In the early phase, it is related with an uncontrolled hyper-inflammation state, whereas in the late phase (>72 h), septic complications play a major role. We review the underlying pathophysiology, the evaluation with different scales and the clinical factors associated with multiorgan fail...

A 41-year-old man with a history of hyperthyroidism had been treated with methimazole and propranolol for the past 2 months. He developed multiorgan dysfunction with acute liver failure, severe lactic acidosis, disseminated intravascular coagulation, heart failure and acute pulmonary edema with rapid deterioration of renal function. The patient had no history of alcoholism, drug abuse, blood tr...

typhoid fever is a common infection in children in developing countries. typhoid fever is a systemic illness which affects many organs. isolated hepatitis, thrombocytopenia and acute renal failure complicating typhoid fever are well known. the potential of multiorgan involvement in typhoid fever - on rare occasions - may occur simultaneously in the same patient.