INTRODUCTION Foam sclerotherapy has gained a great popularity among phlebologists worldwide, although a major lack of homogeneity in the material used to produce sclerosant foam (SF) and to inject SF has been reported. AIMS To highlight the literature data and a few personal clinical and experimental outcomes concerning the main variables in SF production and injection. METHODS A review of ...

Tidal Dwarf Galaxies (TDGs), produced from material expelled in galactic interactions, are well–suited to test the laws of star formation (SF) due to their simple structure, high metallicity – making CO a reliable tracer of the molecular gas content – and recent SF. Here, we study the conditions for the onset of SF and for the rate at which SF proceeds once above a threshold in a small sample o...

OBJECTIVE In synovial fluid (SF) from patients with rheumatoid arthritis (RA), neutrophils are exposed to proinflammatory mediators endowed with either anti-apoptotic or pro-apoptotic properties. We investigated neutrophil apoptosis in the presence of SF from 11 RA patients. METHODS SF was obtained from affected knees of 11 patients with RA. Human neutrophil apoptosis was evaluated by light m...

The orphan nuclear receptor Steroidogenic Factor-1 (SF-1, NR5A1) is a critical regulator of development and homeostasis of the adrenal cortex and gonads. We recently showed that a complex containing E3 ubiquitin ligase RNF31 and the known SF-1 corepressor DAX-1 (NR0B1) interacts with SF-1 on target promoters and represses transcription of steroidogenic acute regulatory protein (StAR) and aromat...

The various molecular weight (MW) regenerated silk fibroins were prepared with different dissolution condition and the effect of MW on the gelation behavior of regenerated aqueous silk fibroin (SF) solution was investigated. The result of gelation time measurement indicated that the gelation of SF aqueous solution was accelerated by the increase of MW and SF concentration. When formic acid was ...

The alloxanized rabbit fed cholesterol develops extreme hyperlipemia and hypercholesteremla and yet develops a lesser degree of atherosclerosis than does the normal animal fed cholesterol. The concentrations of the Sf 12-30 and Sf 20-30 classes of lipoproteins correlate well with athero-sclerosis as finally observed in the alloxanized rabbit, whereas both free and total serum cholesterol correl...

AIM To establish a new and reliable assay for quantification of the soluble fibrin (SF) in combination with that of D-dimer for early diagnosis of venous thromboembolism. METHODS AND SAMPLES The SF assay is based on D-dimer generated after incubation of plasma with tissue-type plasminogen activator (t-PA). SF and standard D-dimer assays, run in blind, were used to test 119 untreated outpatien...

PURPOSE Thioredoxin (Trx) is a multifunctional endogenous redox regulator that protects cells against various types of cellular or tissue stresses. This study was conducted to test whether sulforaphane (SF), a naturally occurring isothiocyanate that is highly concentrated in broccoli sprouts, induces Trx in retinal tissues and whether pretreatment with SF protects against light-induced retinal ...

Steroidogenic factor 1 (SF-1) is essential for the development and function of steroidogenic tissues. Stable incorporation of SF-1 into embryonic stem cells (SF-1-ES cells) has been shown to prime the cells for steroidogenesis. When provided with exogenous cholesterol substrate, and after treatment with retinoic acid and cAMP, SF-1-ES cells produce progesterone but do not produce other steroids...

Chloroethylnitrosoureas (CENUs), which are bifunctional alkylating agents widely used in the clinical treatment of cancer, exert anticancer activity by inducing crosslink within a guanine-cytosine DNA base pair. However, the formation of dG-dC crosslinks can be prevented by O6-alkylguanine-DNA alkyltransferase (AGT), ultimately leading to drug resistance. Therefore, the level of AGT expression ...