The orphan nuclear receptor steroidogenic factor 1 (SF-1) is an essential regulator of endocrine organogenesis, sexual differentiation, and steroidogenesis. SF-1 is a transcriptional regulator of cAMP responsive genes, but the exact mechanisms by which cAMP-dependent PKA modulates SF-1 dependent transcription leading to increased steroidogenic output have not been determined. In this report the...

This paper investigated whether the SF-12 could replace the SF-36 in the measurement of health status among ischaemic heart disease patients. The SF-36 and SF-12 were administered to 105 cardiac patients. The SF-36 summary scores were strongly correlated and similar to the SF-12 summary scores. Also, the SF-12 scores were as powerful as the SF-36 summary scores in discriminating between subgrou...

Three components, SF-973 A, B, and C were obtained from a Streptomyces olivaceus SF-973. SF-973 B catalyzed the converison of inactive SF-973 C (dihydroabikoviromycin) to bioactive SF-973 A (abikoviromycin). Purification of SF-973 B was conducted by sequential chromatographies on columns of DEAE-cellulose, Sephadex G-75, and Sephadex G-100. The enzyme SF-973 B was most active at around pH 7 and...

STUDY OBJECTIVE To determine the involvement in civil society groups (CSGs) and the impact of this on health. DESIGN Case study, cross sectional, self completion questionnaire, and semi-structured interviews. SETTING Residents in two suburbs in Adelaide, South Australia. PARTICIPANTS Every household (1038) received a questionnaire asking the adult with the next birthday to complete it. A ...

BACKGROUND The psychometric properties of the Korean Short Form-12 Health Survey, version 2 (SF-12 v2) have not been assessed in the general population. Therefore, the aim of our study was to evaluate the psychometric properties of the Korean version of the SF-12 v2 in the general population and to provide SF-12 v2 domain scores according to the general characteristics of the study population. ...

Sulfonefluorescein (SF) is a fluorescent organic anion secreted by kidney proximal tubules. The purposes of this study were 1) to quantify accumulation of SF in normal and cystic rat kidneys in vivo and 2) to test whether SF accumulation could be used as a marker for cysts derived from proximal tubules. Male Munich-Wistar rats, normal Han:SPRD rats, and heterozygous Han:SPRD rats with autosomal...

The objective of the present study was to investigate immunoglobulin G (IgG) and IgA antibody immune responses to Porphyromonas gingivalis, Prevotella intermedia, Bacteroides forsythus, and Candida albicans in the sera of patients with rheumatoid arthritis (RA), the synovial fluid (SF) of patients with RA (RA-SF samples), and the SF of patients without RA (non-RA-SF samples). An enzyme-linked i...

Let \(2<n<\omega\). Then \({\sf CA}_n\) denotes the class of cylindric algebras dimension \(n\), RCA}_n\) representable \(\sf CA_n\)s, CRCA}_n\) completely CA}_n\)s, and Nr}_n{\sf CA}_{\omega}(\subseteq {\sf CA}_n\)) \(n\)-neat reducts CA}_{\omega}\)s. The elementary closure CRCA}_n\)s (\(\mathbf{K_n}\)) non-elementary At}({\sf CA}_{\omega})\) are characterized using two-player zero-sum g...

The Dax-1 gene encodes a protein that is structurally related to members of the orphan nuclear receptor superfamily. Dax-1 is coexpressed with another orphan nuclear receptor, steroidogenic factor-1 (SF-1), in the adrenal, gonads, hypothalamus, and pituitary gland. Mutations in Dax-1 cause adrenal hypoplasia congenita, a disorder that is characterized by adrenal insufficiency and hypogonadotrop...

BACKGROUND Psychosocial variables, including stress, emotions, and social factors, may contribute to the association between socioeconomic status (SES) and health. Concepts and methods from interpersonal theory (1) could provide a useful framework for research concerning the roles of psychosocial factors in socioeconomic health disparities. PURPOSE We examined the association between SES and ...