Objective: Brain-derived neurotrophic factor (BDNF) is known to be involved in the plasticity of neurons and pathophysiology of several psychiatric illnesses. The purpose of this study was to determine whether there is an abnormality of plasma BDNF concentrations in patients with somatization disorder, and the alteration after antidepressant treatment. Methods: The 27 patients with somatization...

Objective: Brain-derived neurotrophic factor (BDNF) is known to be involved in the plasticity of neurons and pathophysiology of several psychiatric illnesses. The purpose of this study was to determine whether there is an abnormality of plasma BDNF concentrations in patients with somatization disorder, and the alteration after antidepressant treatment. Methods: The 27 patients with somatization...

background: it is mostly organic diseases that are considered when a neurological sign or symptom is present in the history of a patient; however, there may be psychiatric problems also present which could be missed. we report a case to discuss the possibility of the presence of an organic or psychiatric underlying disorder when facing neurological problems. case presentation: we report a case ...

Objective: Brain-derived neurotrophic factor (BDNF) is known to be involved in the plasticity of neurons and pathophysiology of several psychiatric illnesses. The purpose of this study was to determine whether there is an abnormality of plasma BDNF concentrations in patients with somatization disorder, and the alteration after antidepressant treatment. Methods: The 27 patients with somatization...

BACKGROUND The PHQ-15 is widely used as an open access screening instrument for somatization syndromes in different health care settings, thus far, normative data from the general population are not available. The objectives of the study were to generate normative data and to further investigate the construct validity of the PHQ-15 in the general population. METHODS Nationally representative ...

We compare the prevalence of somatization in women and men with NCCP relation to general Swedish population, analyze overlap between somatization, cardiac anxiety, depressive symptoms, explore variables associated somatization. A cross sectional design is implemented data collected late October 2013 early January 2014 from 552 patients (mean age 64 ​± ​17 years, 51% women) four hospitals southe...

the aetiology behind odor-related chronic somatic symptoms (o-rcss) is unknown, although both immunological and psychiatric causes have been suggested. the aim of this study was to investigate the occurrence of self-reported asthma and hay fever and psychiatric symptoms in individuals having o-rcss compared to individuals with similar chronic somatic symptoms (css) which were not odors-related,...

BACKGROUND Diagnostic criteria for somatization disorder emphasize its early onset and long-term stability. Research assessments of somatization disorder depend on lifetime recall of medically unexplained somatic symptoms. METHODS Longitudinal data from the World Health Organization Psychological Problems in General Health Care study were used to examine stability of somatization disorder and...