1-(1-Pyrrolin-2-yl)-.BETA.-carbolines. Synthesis of eudistomins H, I, and P.
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Synthesis and Leishmanicidal Activity of 1-[5-(5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl]-4-benzoylepiperazines
A series of (5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl derivatives 6a–6e have been synthesized and screened for in vitro anti-leishmanial activity against the promastigote form of L. major. The structure of Schiff bases were confirmed by 1H NMR, IR. Screening results indicate that all of the designed and synthesized final compounds (6a-6e) significantly reduced the viability of promastigotes ...
متن کاملSynthesis and Leishmanicidal Activity of 1-[5-(5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl]-4-benzoylepiperazines
A series of (5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl derivatives 6a–6e have been synthesized and screened for in vitro anti-leishmanial activity against the promastigote form of L. major. The structure of Schiff bases were confirmed by 1H NMR, IR. Screening results indicate that all of the designed and synthesized final compounds (6a-6e) significantly reduced the viability of promastigotes ...
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# 2006 International Union of Crystallography All rights reserved In the crystal structure of the title compound, C16H18N2O2, the indole moiety is nearly planar. The two carbonyl groups are almost perpendicular, with a torsion angle of 105.7 (4) , and the single C—C bond linking the two carbonyl groups is 1.515 (5) Å in length. The molecules are linked together by N—H O intermolecular hydrogen ...
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In the title compound, C(22)H(23)NO, the dihedral angle between the naphthyl ring system and the benzene ring is 73.32 (6)°. An intra-molecular O-H⋯N hydrogen bond stabilizes the mol-ecular conformation. In the crystal structure, mol-ecules are linked by C-H⋯π inter-actions, resulting in zigzag chains parallel to the [10] direction.
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Background: Leukocytospermia is found in both fertile and infertile men with and without evidence of infections of the genital tract. However, despite extensive research done in this subject, the clinical implications of this condition remain unclear. Leukocytes are also commonly found in semen samples, and a level above 1×106/mL is considered pathologic according to WHO criteria. Non-steroidal...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1989
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.37.2596