1018 DIAGNOSTIC AGREEMENT BETWEEN ECHOCARDIOGRAPHY AND SECOND-LEVEL IMAGING TECHNIQUES IN PATIENTS WITH CARDIAC MASSES

Abstract Background Cardiac masses (CMs) are a diagnostic dilemma in clinical practice and require multimodality imaging to assess malignancy, which is essential guide the proper treatment. Aim To define accuracy agreement between echocardiographic features second-level techniques (cardiac computed tomography – CCT or cardiac magnetic resonance CMR) patients with CMs. Methods All consecutive histologically confirmed from January 2004 December 2020, undergoing and/or CMR after assessment were enrolled. Six variables, namely infiltration, polylobate mass, moderate-severe pericardial effusion, inhomogeneity, sessile non-left localization, used predict malignancy. Patients more than 3 of these considered at higher risk For before 2017, choice perform was up cardiologist. Since indication has been result multidisciplinary discussion by Heart Team. A definitive diagnosis achieved histological examination or, case thrombi, radiological evidence thrombus resolution an appropriate anticoagulant The echo-vs-CCT echo-vs-CMR evaluated. Accuracy indicators (sensitivity, specificity, PPV, NPV, Cohen's Kappa coefficient) calculated standard formulas. Results Out 249 CM, 138 underwent 112 CMR, assessment. complete assignment (using cut-off parameters as marker for malignancy) reached 104 out cases (75.4%), ranging 85.1 70.3% benign malignant masses, respectively. On other side, report 93 (83%), 88.7 82% masses. expressed κ echocardiography versus (k=0.73), compared (k=0.61). These results also (87% vs 80%), best values sensitivity, denoting good reliability first 2 techniques. Conclusions multimodal approach mandatory work-up assessment, turned be most accurate investigation discriminate However, when not available patient contraindication, could still reliable.