1283. New Generation Antiviral Conjugate (AVC): Stable, Safe, and Single
نویسندگان
چکیده
منابع مشابه
A New Generation of Antiviral Drugs:
BTD, Ltd. has introduced a new direction in the use of antisense agents in therapeutics that can lead to breakthroughs in the development of antisense drugs. As described in this non confidential summary, it has already resulted in the development of promising antisense antiviral agents, as demonstrated by their significant in vitro effects on hepatitis C virus activity as well as on other viru...
متن کاملA New Generation of Antiviral Drugs
BTD, Ltd. has introduced a new direction in the use of antisense agents in therapeutics that can lead to breakthroughs in the development of antiviral drugs. As described in this non confidential summary, it has already resulted in the development of promising antiviral agents, as demonstrated by their significant in vitro and in vivo effects on hepatitis C virus activity as well as on other vi...
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The metabolism of delamanid (OPC-67683, Deltyba), a novel treatment of multidrug-resistant tuberculosis, was investigated in vitro using plasma and purified protein preparations from humans and animals. Delamanid was rapidly degraded by incubation in the plasma of all species tested at 37 C, with half-life values (hours) of 0.64 (human), 0.84 (dog), 0.87 (rabbit), 1.90 (mouse), and 3.54 (rat). ...
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Vaccines are formulated to generate strong immune responses against administered antigens thereby providing long-term immunity, especially against microbial infections. To achieve this goal, safe and optimal vaccines are designed by developing new generation vaccines with efficacious adjuvants. These vaccines are mainly based on recombinant forms of protein subunits that are purified from molec...
متن کاملNew treatment of hepatitis C (Direct Acting Antiviral)
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with approximately 71 million chronically infected individuals worldwide. Clinical care for the patients with HCV-related liver disease has advanced considerably thanks to an enhanced understanding of the pathophysiology of the disease, and because of developments in diagnostic procedures and improvements in therapy an...
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ژورنال
عنوان ژورنال: Open Forum Infectious Diseases
سال: 2020
ISSN: 2328-8957
DOI: 10.1093/ofid/ofaa439.1466