1713. Impact of False-Positive Low-Titer Cryptococcal Antigen Testing
نویسندگان
چکیده
منابع مشابه
False positive latex tests for cryptococcal antigen in cerebrospinal fluid.
on the instrument, its date, its inventor Lee or the manufacturing or supplying firm ofAL Hawkins Ltd, London. Another machine "The Sedigraph" made by a Swiss firm after the Second World War acted in a similar fashion with rather more sophistication. One of these instruments is also in the collection. The collection of old instruments nlow numbers about 1000 items which, it is hoped, will form ...
متن کاملInactivated pronase as the cause of false-positive results of serum cryptococcal antigen tests.
Four patients who had acquired immunodeficiency syndrome and who were evaluated for headache within a 3-week period had false-positive results of serum cryptococcal antigen tests. This cluster of false-positive test results appeared to be due to inactivation of the pronase vial in the test kit, a cause that has not been reported previously.
متن کاملFalse-positive cryptococcal antigen test associated with use of BBL Port-a-Cul transport vials.
A total of 52 residual CSF and serum specimens, which were originally negative with the Cryptococcal Antigen Latex Agglutination System (CALAS), were shown to become falsely positive after placement in BBL Port-A-Cul anaerobic transport vials. This transport device, although excellent for specimen transportation for subsequent culture, should not be used if cryptococcal antigen testing is needed.
متن کاملNew cause for false-positive results with the cryptococcal antigen test by latex agglutination.
The highly specific and sensitive latex agglutination test for cryptococcal antigen detection in cerebrospinal fluid is routine in many hospitals. Contamination of cerebrospinal fluid by a minute amount of syneresis fluid (surface condensation) from agar gave a strongly positive reaction which was heat stable, was not eliminated by pronase treatment, and was not detected by the normal rabbit gl...
متن کاملFalse-negative cerebrospinal fluid cryptococcal latex agglutination tests for patients with culture-positive cryptococcal meningitis.
Three cases of false-negative cerebrospinal fluid latex agglutination test results for patients with culture-positive cryptococcal meningitis are reported. False-negative results occurred in settings of low cryptococcal antigen concentrations in cerebrospinal fluid and were dependent on the latex agglutination test kit used. Investigation of each case revealed that prozone phenomena or interfer...
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ژورنال
عنوان ژورنال: Open Forum Infectious Diseases
سال: 2019
ISSN: 2328-8957
DOI: 10.1093/ofid/ofz360.1576