2 Case Reports of SAPHO Syndrome.

Kindler Syndrome: 2 Case Reports from India

Kindler syndrome (KS) is a rare autosomal recessive genodermatosis. We report two cases of KS with classical clinical presentations involving skin and mucus membranes. Clinically, both patients had four major features of KS in the form of acral skin blistering, photosensitivity, progressive poikiloderma, and diffuse cutaneous atrophy. Case 1 had associated features in the form of urethral...

SAPHO Syndrome in Childhood. A Case Report

The acronym of SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis and osteitis) combines a cluster of cutaneous and musculoskeletal manifestations, such as hyperostosis of bones of the anterior chest wall associated with acne fulminans and hidradenitis suppurativa. There are no validated diagnostic criteria in children. Nonsteroidal anti-inflammatory drugs are not always sufficient, and ...

SAPHO Syndrome

SAPHO syndrome in childhood. A case report.

The acronym of SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis and osteitis) combines a cluster of cutaneous and musculoskeletal manifestations, such as hyperostosis of bones of the anterior chest wall associated with acne fulminans and hidradenitis suppurativa. There are no validated diagnostic criteria in children. Nonsteroidal anti-inflammatory drugs are not always sufficient, and ...

SAPHO Syndrome

In 1987, Chamot et al attempted to unify the various descriptions of osteoarticular disease associated with skin manifestations into a syndrome with the acronym SAPHO: synovitis, acne, pustulosis, hyperostosis, and osteitis (Chamot et al., 1987). Furthermore, the clinical feature of aseptic chronic recurrent multiple osteomyelitis (CRMO) accompanied by pustulosis with its typical presentation i...