(212) Do Women with Remittent-Recurrent Multiple Sclerosis (RRMS) have Higher Prevalence of Sexual Dysfunction? A Transversal Analytic Study of Brazilian Patients

Abstract Introduction Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) which characterized by inflammation, demyelination, axon loss and gliosis. More than 2.8 million people worldwide are affected MS, mainly young at reproductive age with significant lifelong repercussions. Among several MS symptoms, sexual dysfunction (SD) one most neglected during routine clinical care. Objective We aimed to evaluate prevalence SD in female patients diagnosed Remitting-Recurrent (RRMS), compared control group women without comorbidity stratify different causes factors that can lead SD. Methods This transversal analytic study was carried out Santa Casa de São Paulo, Faculdade Ciências Médicas, Paulo/SP, Brazil, between November 2020 2021. Our sample included 80 RRMS 106 group. have collected demographic data all participants underwent neurological examination. Questionnaires about (Multiple Sclerosis Intimacy Sexuality Questionnaire - MSISQ-19- Female Sexual Function Index FSFI) depression anxiety (Hospital Anxiety Depression Scale – HADS, Beck's Inventory BDI- Beck inventory-BAI) were applied. Baseline characteristics reported as proportions mean ± or median IQR appropriate according distribution. The presence described evaluated qualitative parameters association use Chi-square tests exact verified quantitative t-Student Mann-Whitney tests. Statistical analyses performed using IBM-SPSS for Windows versão 20.0 Results observed high both groups (43.4% 38.8%, respectively, group) FSFI analysis. A higher statistically (56.3%) when MSISQ-19 tool assessing sexuality this population, comparison scale (p = 0.016). anxious (53.2% 47.2% BAI) depressive symptoms (37.2% 38.8% group, BDI) similar > 0.05). Both revealed rates symptoms. There no other associated on Conclusions did not find Nevertheless we found specific (MSISQ-19) able reveal Besides that, also related SD, so strongly suggest healthcare providers assess treat these comorbidities paralel approach questionnaire deal their function. Disclosure No