2P2Idb: a structural database dedicated to orthosteric modulation of protein–protein interactions
نویسندگان
چکیده
منابع مشابه
2P2Idb v2: update of a structural database dedicated to orthosteric modulation of protein–protein interactions
2P2Idb is a hand-curated structural database dedicated to protein-protein interactions with known small molecule orthosteric modulators. It compiles the structural information related to orthosteric inhibitors and their target [i.e. related 3D structures available in the RCSB Protein Data Bank (PDB)] and provides links to other useful databases. 2P2Idb includes all interactions for which both t...
متن کامل2P2Idb: a structural database dedicated to orthosteric modulation of protein–protein interactions
Protein-protein interactions are considered as one of the next generation of therapeutic targets. Specific tools thus need to be developed to tackle this challenging chemical space. In an effort to derive some common principles from recent successes, we have built 2P2Idb (freely accessible at http://2p2idb.cnrs-mrs.fr), a hand-curated structural database dedicated to protein-protein interaction...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2012
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/gks1002