5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Physiology and Toxicology
نویسندگان
چکیده
منابع مشابه
The effect of DL-5-hydroxytryptophan (5-HTP) on plasma prolactin in pituitary stalk sectioned rats.
5-HTP (5 mg/100 g body weight), a precursor of serotonin, was administered intravenously to pituitary stalk sectioned rats. Plasma prolactin levels were initially increased 30 and 60 min after the injection of 5-HTP and thereafter decreased. Pituitary prolactin content was decreased 60 min after the stalk section as compared to those seen following sham operation. The treatment of 5-HTP induced...
متن کاملEffect of hypothalamic surgery on prolactin release induced by 5-hydroxytryptophan (5-HTP) in rats.
Intravenous injections of varying doses of 5-HTP (1, 3 and 5 mg/100 g body wt), a precursor of serotonin, caused a significant and dose-related increase in plasma prolactin concentrations in urethane-anesthetized rats. Increases in plasma prolactin concentrations caused by 5-HTP (1 mg/100 g body wt iv) were abolished by the concomitant administration of L-DOPA (2 mg/100 g body wt iv). Plasma pr...
متن کامل5-HTP efficacy and contraindications
L-5-hydroxytryptophan (5-HTP) is the immediate precursor of serotonin. It is readily synthesized into serotonin without biochemical feedback. This nutrient has a large and strong following who advocate exaggerated and inaccurate claims relating to its effectiveness in the treatment of depression and a number of other serotonin-related diseases. These assertions are not supported by the science....
متن کاملTryptophan and 5-hydroxytryptophan for depression.
BACKGROUND 5 Hydroxytryptophan (5-HTP) and tryptophan are so-called natural alternatives to traditional antidepressants, used to treat unipolar depression and dysthymia. OBJECTIVES To determine whether 5-HTP and tryptophan are more effective than placebo, and whether they are safe to use to treat depressive disorders in adults. SEARCH STRATEGY Trials were searched in computerized general (M...
متن کاملPrecancerous Loss of 5-Hydroxytryptophan Decarboxylase Activity
The purpose of this experimental work was to determine whether the precancerous loss of rat liver 5-hydroxytryptophan (5-HT) decarboxylase was associated with sequential atrophic alterations preceding hepatocarcinogenesis. To test whether such an association existed, three experimental conditions were employed in which hepato carcinogenesis was either markedly delayed or prevented. Under all th...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2020
ISSN: 1422-0067
DOI: 10.3390/ijms22010181