5HT1BReceptor Agonists Inhibit Light-Induced Phase Shifts of Behavioral Circadian Rhythms and Expression of the Immediate–Early Genec-fosin the Suprachiasmatic Nucleus
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چکیده
منابع مشابه
The relation between light-induced discharge in the suprachiasmatic nucleus and phase shifts of hamster circadian rhythms.
The role of neurophysiological activation of suprachiasmatic nucleus (SCN) cells in phase shifting the circadian pacemaker of the hamster was investigated in a combined behavioural and electrophysiological study. An electrophysiological study examined the relation between the pattern of light presentation and the induced discharge rate in the SCN. Behavioural experiments examined the relation b...
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We analyzed the phase shifts of oscillated transcripts relative to the timing of phase-reset stimuli. Oscillations in gene expression profiles were extracted using the fast Fourier transform and fitted by sine curve with random periods. The phase differences among multiple phase-reset conditions were analyzed to elucidate the mechanism of the core circadian clock. For the expression profiles, c...
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Ontogeny of Circadian Rhythms and Synchrony in the Suprachiasmatic Nucleus.
In mammals, the suprachiasmatic nucleus (SCN) of the hypothalamus coordinates daily rhythms including sleep-wake, hormone release, and gene expression. The cells of the SCN must synchronize to each other to drive these circadian rhythms in the rest of the body. The ontogeny of circadian cycling and intercellular coupling in the SCN remains poorly understood. Recent in vitro studies have recorde...
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Regulated expression of a core set of clock genes is the basis of circadian timekeeping in vertebrates, as in other organisms. Clock genes are defined as being necessary to generate normal circadian rhythms, near 24 h oscillations in biological processes. With the enlargement of the brain in vertebrates, control of circadian rhythms became centralized. In lower vertebrates, such as fishes, liza...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 1996
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.16-24-08208.1996