712: Comparison of 4F-PCC for Reversal of DOAC Versus Warfarin-Associated Intracranial Hemorrhage

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Poor prognosis in warfarin-associated intracranial hemorrhage despite anticoagulation reversal.

BACKGROUND AND PURPOSE Anticoagulant-associated intracranial hemorrhage (aaICH) presents with larger hematoma volumes, higher risk of hematoma expansion, and worse outcome than spontaneous intracranial hemorrhage. Prothrombin complex concentrates (PCCs) are indicated for urgent reversal of anticoagulation after aaICH. Given the lack of randomized controlled trial evidence of efficacy, and the p...

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Challenging Management of Warfarinised Patients with Intracranial Hemorrhage Following a Head Injury: A Major Medical Dilemma

Introduction:The use of anticoagulant and ant platelet medications, especially warfarin and clopidogrel, is on a growing trend. Warfarin usage is commonly accompanied with hemorrhagic complications resulting in a noticeable mortality rate. Patient's ant coagulated with warfarin suffers from intracranial hemorrhage after a head injury. Materials and Methods: For the purpose of the study, the rel...

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Location and Characteristics of Warfarin Associated Intracranial Hemorrhage

OBJECTIVE In the so-called primary intracerebral hemorrhage (ICH), lobar and deep ICH were mainly due to cerebral amyloid angiopathy and deep perforating arterial disease. Our aim was to identify specifics of warfarin associated ICH (WAICH) and to focus on differences in susceptibility to warfarin according to the underlying vasculopathies, expressed by ICH location. MATERIALS AND METHODS We ...

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A 27-yr-old woman who had been taking warfarin for 10 yr after mitral valve replacement became pregnant. After knowing her pregnancy, she received heparinization for nine weeks instead of warfarin, and took oral anticoagulant again. At 24 weeks of gestation, fetal ultrasound and MRI showed a left subdural hematoma, and the pregnancy was terminated. Subdural hematoma was demonstrated on autopsy....

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ژورنال

عنوان ژورنال: Critical Care Medicine

سال: 2020

ISSN: 0090-3493

DOI: 10.1097/01.ccm.0000728736.27563.c8