A BOLD Look at Cerebral Oxygen Consumption
نویسندگان
چکیده
منابع مشابه
Investigation of BOLD signal dependence on cerebral blood flow and oxygen consumption: the deoxyhemoglobin dilution model.
The relationship between blood oxygenation level-dependent (BOLD) MRI signals, cerebral blood flow (CBF), and oxygen consumption (CMR(O2)) in the physiological steady state was investigated. A quantitative model, based on flow-dependent dilution of metabolically generated deoxyhemoglobin, was validated by measuring BOLD signals and relative CBF simultaneously in the primary visual cortex (V1) o...
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HE BLOOD FLOW AND OXYGEN METABOLISM of the human brain has been studied intensively since Kety developed the inert gas method in 1945. More than 200 clinical studies employing this method have been published so far, and now the former terra incognita is well mapped out. The information gained from all these studies will form the subject of the present review. It will also include, however, the ...
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C URRENTLY there is widespread interest in the physiologic effects of cold, and in the use of hypothermia with surgery (I, 2). Although no gross neurologic derangements have been observed following the application of this technique in man and experimental animals (3, 4), it seemed appropriate that a special study be made of the effects of hypothermia on cerebral physiology. Cerebral blood flow,...
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BACKGROUND AND PURPOSE The aura phase of migraine is associated with focal blood flow changes, but it has been largely unknown whether these changes are correlated to changes in the cerebral metabolism. METHODS Eight patients required carotid angiography for evaluation of transient neurological attacks. Cerebral blood flow (CBF) results, angiography, and clinical observations subsequently sug...
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ژورنال
عنوان ژورنال: Neurosurgery
سال: 2003
ISSN: 0148-396X,1524-4040
DOI: 10.1227/01.neu.0000309172.50740.b4