A Controlled Impact of Optic Nerve as a New Model of Traumatic Optic Neuropathy in Mouse
نویسندگان
چکیده
منابع مشابه
Traumatic ischaemic optic neuropathy.
Persistent profound visual loss following contusion of the globe or ocular adnexae has been well documented, the visual loss being attributed to haemorrhage into, or contusion of, the optic nerve, or to interference with the blood supply of the eye. The patient described below presented after a contusion of the eye and orbit, with the clinical picture of ischaemic optic neuropathy presumably re...
متن کاملIndirect traumatic optic neuropathy
Indirect traumatic optic neuropathy (ITON) refers to optic nerve injury resulting from impact remote to the optic nerve. The mechanism of injury is not understood, and there are no confirmed protocols for prevention, mitigation or treatment. Most data concerning this condition comes from case series of civilian patients suffering blunt injury, such as from sports- or motor vehicle-related concu...
متن کاملTraumatic optic neuropathy.
Introduction: Traumatic optic nerve damage after craniofacial injury was first described by Hippocrates.1 Although the natural history of traumatic optic neuropathy is unknown, recent studies suggest that high dose steroids and, even surgical decompression of the optic canal or the nerve sheath (in cases of nerve sheath hematoma) may restore vision in selected patients.2-8 The commonest cause o...
متن کاملTraumatic Optic Neuropathy [TON] - A Review
It is generally presumed that penetrating injuries of the orbit are associated with direct optic nerve injury. The incidence of TON after craniofacial trauma has been reported to be 0.5-1.5 % in older series. However, recent surveys report a higher figure; 2-5 % . This increased incidence may represent the diagnosis of subtle forms of TON closer to the time of injury. These types of cases appea...
متن کاملHyperintense Optic Nerve due to Diffusion Restriction: Diffusion-Weighted Imaging in Traumatic Optic Neuropathy.
BACKGROUND AND PURPOSE Abnormal signal intensity of the optic nerve due to diffusion restriction may be seen in traumatic optic neuropathy. In addition to evaluating optic nerve hyperintensity on diffusion-weighted imaging, we compared the group differences of ADC values between the injured and uninjured contralateral nerve and identified the relation between measured ADC values and admission v...
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ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2018
ISSN: 1552-5783
DOI: 10.1167/iovs.18-24773