A dose escalation, safety, and tolerability study of MN-029 in patients with advanced solid tumors
نویسندگان
چکیده
منابع مشابه
A dose-escalation and pharmacokinetic study of gemcitabine and oxaliplatin in patients with advanced solid tumors.
BACKGROUND Gemcitabine and oxaliplatin have broad antineoplastic activity and favorable toxicity. We conducted a phase I study to determine the maximum tolerated doses (MTDs) and dose-limiting toxicities (DLTs) of the combination in patients with advanced solid tumors. PATIENTS AND METHODS Sixty-eight patients with advanced stage solid tumors were enrolled. Treatment was first-line for 35% of...
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ژورنال
عنوان ژورنال: Investigational New Drugs
سال: 2009
ISSN: 0167-6997,1573-0646
DOI: 10.1007/s10637-009-9264-2