A general, modular method for the catalytic asymmetric synthesis of alkylboronate esters

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A general, modular method for the catalytic asymmetric synthesis of alkylboronate esters.

Alkylboron compounds are an important family of target molecules, serving as useful intermediates, as well as end points, in fields such as pharmaceutical science and organic chemistry. Facile transformation of carbon-boron bonds into a wide variety of carbon-X bonds (where X is, for example, carbon, nitrogen, oxygen, or a halogen), with stereochemical fidelity, renders the generation of enanti...

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ژورنال

عنوان ژورنال: Science

سال: 2016

ISSN: 0036-8075,1095-9203

DOI: 10.1126/science.aai8611