A Ku Bridge over Broken DNA

اسناد مشابه

• Polymerases in Nonhomologous End Joining: Building a Bridge over Broken Chromosomes

  مقاله‌ی دسترسی آزاد۲۰۱۱Antioxidants & Redox SignalingDale A.Ramsden

• Ultrafine anaphase bridges, broken DNA and illegitimate recombination induced by a replication fork barrier

  سند علمی۲۰۱۱Nucleic acids researchSevil Sofueva, Fekret Osman, Alexander Lorenz, Roland Steinacher

  Most DNA double-strand breaks (DSBs) in S- and G2-phase cells are repaired accurately by Rad51-dependent sister chromatid recombination. However, a minority give rise to gross chromosome rearrangements (GCRs), which can result in disease/death. What determines whether a DSB is re

• Erratum: Corrigendum: Sliding sleeves of XRCC4–XLF bridge DNA and connect fragments of broken DNA

  مقاله‌ی دسترسی آزاد۲۰۱۷NatureInekeBrouwer, GerritSitters, AndreaCandelli, Stephanie J.Heerema

• Surface salt bridges modulate the DNA site size of bacterial histone-like HU proteins.

  سند علمی۲۰۰۵The Biochemical journalEdwin Kamau, Nick D Tsihlis, L Alice Simmons, Anne Grove

  Bacterial histone-like DNA-binding proteins are best known for their role in compacting the genomic DNA. Of these proteins, HU is ubiquitous and highly conserved across the eubacterial kingdom. Using the HBsu (Bacillus subtilis-encoded HU homologue) as a model, we explore here th

• KAP-1 promotes resection of broken DNA ends not protected by γ-H2AX and 53BP1 in G₁-phase lymphocytes.

  سند علمی۲۰۱۴Molecular and cellular biologyAnthony T Tubbs, Yair Dorsett, Elizabeth Chan, Beth Helmink

  The resection of broken DNA ends is required for DNA double-strand break (DSB) repair by homologous recombination (HR) but can inhibit normal repair by nonhomologous end joining (NHEJ), the main DSB repair pathway in G1-phase cells. Antigen receptor gene assembly proceeds through

• Multi-site H-bridge breathers in DNA

  سند علمی۲۰۰۲D. Hennig

  We investigate the formation process of nonlinear vibrational modes representing broad H-bridge multi–site breathers in DNA. Within a network model of the DNA double helix we take individual motions of the bases within the base pair plane into account. The resulting H-bridge defo